Type: Conference Paper
A Loop-Mediated Isothermal Amplification (Lamp)-Based Point-of-Care System for Rapid on-Site Clinical Detection of Sars-Cov-2 Viruses
Journal: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (10846999)Year: 2023Volume: 2023Issue: Pages: 437 - 439
Nguyen, TrieuVinayaka, Aaydha ChidambaraHuynh, Van NgocAndreasen, Sune ZoëgaGlaby M.aBang, Dang DuongWolff, Anders
DOI:10.1109/MEMS49605.2023.10052467Language: English
Abstract
In the ongoing COVID-19 pandemic, sensitive and rapid on-site detection of the SARS-CoV-2 coronavirus has been one of crucial objectives. A point-of-care (PoC) device called PATHPOD for quick, on-site detection of SARS-CoV-2 employing a real-time reverse-transcription loop-mediated isothermal amplification (RT-rLAMP) reaction on a polymer cartridge. The PATHPOD consists of a standalone device (weighing under 1.2 kg) and a cartridge, and can identify 10 distinct samples and 2 controls in less than 50 minutes. The PATHPOD PoC system is fabricated and clinically validated for the first time in this work © 2023 IEEE.