Background
Type: Article

An efficient and facile one-step synthesis of highly substituted thiophenes

Journal: Tetrahedron (14645416)Year: 12 July 2004Volume: 60Issue: Pages: 6085 - 6089
Matloubi Moghaddam, FirouzZali Boeini H.a
DOI:10.1016/j.tet.2004.05.072Language: English

Abstract

An efficient one-step method for the synthesis of fully substituted thiophenes, from thiomorpholides and α-halo ketones, was developed. A mechanism has also been proposed for the course of reaction. © 2004 Elsevier Ltd. All rights reserved.