Highly efficient synthesis of thieno[2,3-b]indole derivatives

Abstract

Thieno[2,3-b]indole derivatives were efficiently prepared via the reaction of 1,3-dihydro-2H-indole-2-thiones with α-bromo-substituted ketones or aldehydes and in the presence of Et3N (Scheme 2 and Table). The reaction took place under very mild conditions and in short times with good to excellent yields. © 2009 Verlag Helvetica Chimica Acta AG.