Mild, efficient and selective opening of epoxides with alcohols catalyzed by ceric(iv) ammonium nitrate.

Abstract

Commercially available Ceric(IV) Ammonium Nitrate (CAN) catalyzes nucleophilic ring opening of epoxides in primary, secondary and tertiary alcohols under mild conditions. The corresponding β -alkoxy-alcohols were obtained with high regio and stereoselectivity in high yields. © 1990, Taylor & Francis Group, LLC. All rights reserved.