One-step synthesis of azole- and benzazole-based sulfonamides in aqueous media

Abstract

Several benzazoles (benzoxazoles, benzothiazoles, and benzimidazoles) and azoles (1H-1,2,4-triazole-5(4H)-thiones and 1,2,4-oxadiazoles) bearing a sulfonamide moiety were efficiently prepared via the reactions of dimethyl (arylsulfonyl) dithioimidocarbonate derivatives and their 2-aminobenzene precursors, thiosemicarbazides, and amidoximes, respectively, in the presence of K2CO3 as a base in aqueous ethanol (25 %) as a green media in moderate to excellent yields. © 2015, Springer International Publishing Switzerland.