Background
Type: Article

Synthesis of 3-substituted indoles promoted by pulverization-activation method catalyzed by Bi(NO3)3·5H2O

Journal: Journal of Heterocyclic Chemistry (0022152X)Year: March/April 2008Volume: 45Issue: Pages: 377 - 381
Khodaei M.M.Mohammadpoor Baltork I.aMemarian H.R. Khosropour A.R. Nikoofar K. Ghanbary P.
DOI:10.1002/jhet.5570450213Language: English

Abstract

(Chemical Equation Presented) A new, facile, efficient, "green" and chemoselective procedure for the synthesis of indole derivatives has been developed with pulverization-activation method catalyzed by Bi(NO 3)3·5H2O (PAMC- Bi(NO3) 3·5H2O) through grinding of indoles with aldehydes or Michael acceptors in the presence of catalytic amounts of Bi(NO 3)3·5H2O under solvent-free conditions.