Background
Type: Review

A Narrative Review of Quercetin’s Role as a Bioactive Compound in Female Reproductive Disorders

Journal: Nutrients (20726643)Year: 2025Volume: Issue: 7Pages: 3159 - 3171
Khamineh Y. Ghiasvand M. Panahi-Alanagh S. Rastegarmand P. Zolghadri S. Stanek A.Rismanchian M.Ebadi A.a Amoosoltani M. Fathi M.
All Open Access; Gold Open AccessDOI:10.3390/nu17071118Language: English

Abstract

Lifestyle, nutrition, and metabolic status are central to maintaining women’s reproductive health. With the rising prevalence of infertility, the need for effective strategies to preserve and enhance women’s reproductive well-being has become increasingly urgent. Quercetin, a plant-derived polyphenol, has attracted growing interest for its potential to support reproductive health, regulate the hormonal balance, and improve fertility. This narrative review examines Quercetin’s role in women’s reproductive health and delineates its possible mechanisms of action in female reproductive system disorders, including polycystic ovary syndrome, recurrent miscarriage, and cervical, ovarian, and endometrial cancer (EC). By highlighting the biological pathways through which quercetin may exert its effects, this article underscores the need for further research and clinical trials to validate its therapeutic potential and its applications as a bioactive compound in foods aimed at enhancing women’s reproductive health. © 2025 by the authors.


Author Keywords

female reproductive disordersgynecological cancerspolycystic ovary syndromepregnancy lossquercetinBiosynthesisClinical trialDocetaxelPaclitaxelTaxoidsToxicologyHGF1-P153 cell lineMicropowderMTT assayNanopowderBiosynthesisClinical trialDocetaxelPaclitaxelTaxoidsToxicologyHGF1-P153 cell lineMicropowderMTT assayNanopowderBalo's concentric sclerosisdemyelinationmagnetic resonance imagingmultiple sclerosiscaracterísticas tafonómicasgusanos poliquetosIsla de Qeshmostracodsostrácodospectinidspectínidospolychaete wormsQeshm Islandtaphonomic featuresdualismemergentismmindneuropsychiatric disorderssoul

Other Keywords

Abortion, HabitualFemaleGenital Diseases, FemaleHumansInfertility, FemalePolycystic Ovary SyndromeQuercetinReproductive Healthpolyphenolquercetinquercetinadultendometrium cancerfemalefemale genital systemfemale genital tract cancergenital system diseasehumanovary polycystic diseaseprevalencerecurrent abortionreproductive healthreviewspontaneous abortiontherapydrug therapyfemale infertilitygynecologic diseaseovary polycystic diseaseBiochemistryCell cultureDiseasesDrug interactionsEnvironmental impactCancer ChemotherapyClinical trialDocetaxelMicrotubulesNational Cancer InstitutePaclitaxelRelated compoundsTaxoidsToxicologyYew treeChemotherapybiomaterialglassmicropowder bioactive glassnanopowder bioactive glassunclassified drugarticlebiocompatibilitybiological activitycell proliferationcell survivalcell viabilitycontrolled studycytotoxicityfibroblasthumanhuman cellparticle sizeBiochemistryCell cultureDiseasesDrug interactionsEnvironmental impactCancer ChemotherapyClinical trialDocetaxelMicrotubulesNational Cancer InstitutePaclitaxelRelated compoundsTaxoidsToxicologyYew treeChemotherapybiomaterialglassmicropowder bioactive glassnanopowder bioactive glassunclassified drugarticlebiocompatibilitybiological activitycell proliferationcell survivalcell viabilitycontrolled studycytotoxicityfibroblasthumanhuman cellparticle sizeBrainDemyelinating DiseasesDiffuse Cerebral Sclerosis of SchilderHumansMagnetic Resonance ImagingMultiple SclerosisMyelin Sheathalemtuzumabazathioprinebeta1a interferoncorticosteroidcyclophosphamidefingolimodfluorodeoxyglucoseimmunoglobulinimmunosuppressive agentmethylprednisolonemitoxantronenatalizumabautologous stem cell transplantationBalo concentric sclerosiscerebrospinal fluid analysisclinical featuredifferential diagnosisdisease associationfollow upimmunosuppressive treatmentneuroimagingnuclear magnetic resonance imagingpathogenesisPelizaeus Merzbacher diseaseplasma exchangepolymerase chain reactionpositron emission tomographyprevalencepriority journalprognosisReviewdemyelinating diseasepathologypathophysiologyproceduresSchilder disease