Type: Article
An Efficient and Selective Solid State Oxidation of Thiols to Disulfides with Quinolinium Fluorochromate on Silica Gel
Journal: Monatshefte fur Chemie (00269247)Year: 2003/12/01Volume: Issue: 12
DOI:10.1007/s00706-003-0073-6Language: English
Abstract
Various kinds of aliphatic (cyclic and acyclic), aromatic, and heterocyclic thiols are converted into the corresponding disulfides by quinolinium fluorochromate (QFC) on silica-gel in excellent yields. Selective oxidation of thiols in the presence of sulfides is also achieved under solid phase conditions.
Author Keywords
ChemoselectivityOxidationsQuinolinium fluorochromateSolid stateThiols1h benzimidazole 2 thiol2 pyridinethiol2 sulfanylacetic acid4 chlorobenzenethiol4 methylbenzenethiolaliphatic compoundaromatic compoundbenzthiazole 2 thiolbenzylhydrosulfidebutanethiolchromic acidcyclohexanethioldisulfideheterocyclic compoundoctanethiolquinolinium fluorochromatesilica gelthiol derivativethiophenolunclassified drug