3-carboxypyridinium chlorochromate (CPCC): A mild, efficient and inexpensive reagent for oxidative deprotection of trimethylsilyl and tetrahydropyranyl ethers under non-aqueous conditions

Abstract

Primary and secondary trimethylsilyl and tetrahydropyranyl (THP) ethers are converted to their carbonyl compounds efficiently using 3- carboxypyridinium chlorochromate. Trimethylsilyl ethers are oxidized selectively in the presence of tetrahydropyranyl ethers.