Deprotection of trimethylsilyl ethers to corresponding alcohols promoted by silica chloride: A heterogeneous and eco-friendly protocol

Abstract

Silica chloride as an efficient solid acid can serve as an eco-friendly and high-capacity reagent for the deprotection of trimethylsilyl ethers to their corresponding alcohols under mild and heterogeneous conditions. The yields are excellent and the procedure is simple and convenient, with the higher catalytic efficiency of a heterogeneous system.