Efficient synthesis of imidazo[2,1-b][1,3]benzothiazoles and 9H-imidazo-[1,2-a][1,3]benzimidazoles under solvent-free conditions

Abstract

An efficient synthesis of imidazo[2,1-b][1,3]benzothiazoles and 9H-imidazo[1,2-a][1,3]benzimidazoles is described from a novel multicomponent reaction between 2-aminobenzothiazoles or 2-aminobenzimidazole, benzaldehydes, and imidazoline-2,4,5-tri-one under solvent-free conditions. © Georg Thieme Verlag Stuttgart.