Type: Article
Prophage and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus strains in Iran
Journal: Archives of Virology (03048608)Year: 2012/09/01Volume: 157Issue: 9Pages: 1807 - 1811
DOI:10.1007/s00705-012-1361-4Language: English
Abstract
A total of 114 isolates of methicillin-resistant Staphylococcus aureus (MRSA) were collected from hospitals in Tehran, Iran. A multiplex PCR was designed to examine the presence of six different prophage classes. The results showed high diversity of bacteriophages, with four different prophage types and eight prophage patterns. An important S. aureus phage coding for several virulence factors, Φ-77-like phage, was detected in 97 % of the isolates. We found a high rate of resistance of MRSA isolates to penicillin, ciprofloxacin, tobramycin and kanamycin. This is the first study showing high prevalence and diverse bacteriophage populations in MRSA strains in Iranian hospitals. © 2012 Springer-Verlag.
Author Keywords
Φ-77-like phageIranMRSAProphage pattern
Other Keywords
Anti-Bacterial AgentsDrug Resistance, Multiple, BacterialGenetic VariationHospitalsHumansIranMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsProphagesStaphylococcal InfectionsStaphylococcus PhagesVirulence Factorsmethicillin resistant Staphylococcus aureusStaphylococcus aureusantiinfective agentvirulence factorarticledrug effectgenetic variabilitygeneticshospitalhumanisolation and purificationmicrobiological examinationmicrobiologymultidrug resistanceprophageStaphylococcus infectionStaphylococcus phage