A facile synthesis of 1,2-azidoalcohols by (TBA) 4PFeW 11O39•3H2O-catalyzed azidolysis of epoxides with NaN3

Abstract

The catalytic efficiency of transition metal substituted polyoxometalates in the azidolysis of 1,2-epoxides has been studied in acetonitrile/water, using NaN3 as the source of the azido group. The reaction is regioselective and afforded the corresponding products in high to excellent yields under mild reaction conditions. Fe (III) substituted polyoxometalate was identified as the optimal catalyst. © Springer Science+Business Media, LLC 2007.