Electrochemical characterization of in situ functionalized gold cysteamine self-assembled monolayer with 4-formylphenylboronic acid for detection of dopamine

Abstract

Functionalization of gold cysteamine (Au-CA) self-assembled monolayer with 4-formylphenylboronic acid (BA) via Schiff's base formation, through in situ method to fabricate Au-CA-BA electrode is presented and described. The fabricated electrode was used as a novel sensor for accumulation and determination of dopamine (DA). The accumulation of DA as a diol on the topside of Au-CA-BA as a Lewis acid, was performed via esterification (Au-CA-BA-DA), and followed for determination of DA. Functionalization, characterization, and determination steps were probed by electrochemical methods like cyclic voltammetry and electrochemical impedance spectroscopy. The data will be presented and discussed from which a new sensor for DA is introduced. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.