Type: Article
Efficient and eco-friendly syntheses of 1,5-benzothiazepines and 1,5-benzodiazepines catalyzed by [Hmim][NO3] under mild conditions
Journal: Journal of Heterocyclic Chemistry (0022152X)Year: January 2014Volume: 51Issue: Pages: 138 - 150
Loghmani-Khouzani H. Tamjidi P.Mohammadpoor Baltork I.a Yaeghoobi M. Abdul Rahman N. Khosropour A.R.Moghadam M.aTangestaninejad S.aMirkhani V.aHabibi M.H.
DOI:10.1002/jhet.1827Language: English
Abstract
This article presents a synthetic method and reaction mechanism of the 1,5-benzothiazepines and 1,5-benzodiazepines derivatives. In this research, 36 thiazepines and diazepines (mostly new) with a new method have been prepared and their structures have been characterized by spectroscopic methods. Crystal structures of a new thiazepine and diazepine (seven-membered rings) have also been determined and compared with thiazine (six-membered ring). In this method, N-methylimidazolium nitrate [Hmim][NO3] has been used as a catalyst that acts as an environmental friendly system. © 2013 HeteroCorporation.