Background
Type: Article

Green and diastereoselective synthesis of trans-3-(5-methylisoxazol-3-yl)-3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazines

Journal: Iranian Journal Of Catalysis (23454865)Year: 1 June 2014Volume: 4Issue: Pages: 133 - 141
Language: English

Abstract

Reaction between aromatic aldehydes and 3-methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields. © 2014 Islamic Azad University.