Isocyanide-catalyzed reaction of tetracyanoethylene and activated 1,3-dicarbonyl CH-acid compounds: A rapid and efficient synthesis of pyran annulated heterocyclic systems

Abstract

An isocyanide-catalyzed reaction between tetracyanoethylene and various activated CH-acid compounds to afford the corresponding pyran annulated heterocyclic ring systems, in high yield at room temperature within a few minutes, is described. To the best of our knowledge, this is the first example in which isocyanide functions as only a catalyst but not a reagent. Copyright © Taylor & Francis Group, LLC.