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Rapid and efficient synthesis of 2-imidazolines and bis-imidazolines under ultrasonic irradiation

Journal: Tetrahedron Letters (00404039)Year: 27 March 2006Volume: 47Issue: Pages: 2129 - 2132
Mirkhani V.aMoghadam M.aTangestaninejad S.aKargar H.
a :University of Isfahan - IRAN(IR) - Isfahan
DOI:10.1016/j.tetlet.2006.01.127Language: English

Abstract

Rapid and efficient preparation of 2-imidazolines and bis-imidazolines by reaction of ethylenediamine with nitriles in the presence of catalytic amounts of sulfur under ultrasonic irradiation is reported. The advantages of this system are short reaction times, high yields and the ability to carry out large scale reactions. © 2006 Elsevier Ltd. All rights reserved.