Type: Article

Dehydrogenation of 2-imidazolines with sodium periodate catalyzed by manganese(III) tetraphenylporphyrin

Journal: Bioorganic and Medicinal Chemistry Letters (0960894X)Year: 2011/04/01Volume: Issue: 7

Kargar H.Moghadam M.^aMirkhani V.^aTangestaninejad S.^aMohammadpoor Baltork I.^a

a :University of Isfahan - IRAN(IR) - Isfahan

DOI:10.1016/j.bmcl.2011.01.126Language: English

Abstract

In the present work, dehydrogenation of 2-substituted imidazolines with sodium periodate in the presence of tetraphenylporphyrinatomanganese(III) chloride, [Mn(TPP)Cl], is reported. A wide variety of 2-imidazolines efficiently converted to their corresponding imidazoles by [Mn(TPP)Cl]/NaIO4 catalytic system at room temperature in 1:2, CH3CN/H2O mixture. The effect of reaction parameters such as kind of solvent and catalyst amount was also investigated. © 2011 Elsevier Ltd. All rights reserved.