Type: Article
Solvent-free synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives through a one-pot three-component reaction
Journal: Molecular Diversity (13811991)Year: 2021/05/01Volume: 25Issue: 2Pages: 1123 - 1130
Alizadeh-Kouzehrash M.Rahmati A.a
DOI:10.1007/s11030-020-10052-yLanguage: English
Abstract
Abstract: Some 5-substituted 3-aminopyrazoles were used for the synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives via a mild and efficient one-pot three-component reaction with 2-formylbenzoic acid and different CH-acids under solvent-free condition. Graphic abstract: [Figure not available: see fulltext.]. © 2020, Springer Nature Switzerland AG.
Author Keywords
Heterocyclic compoundsIsoindolineMulticomponent reactionsPyrazole
Other Keywords
CatalysisGreen Chemistry TechnologyIsoindolesPyrazolesQuinazolinesbenzoic acid derivativeindole derivativeisoindolo[2,1 c]pyrazolo[1,5 a]quinazoline derivativepyrazolo[2,3]pyrimido[6,1 a]isoindol derivativequinazoline derivativesolventunclassified drugisoindole derivativepyrazole derivativeArticlecarbon nuclear magnetic resonancechemical reactionchemical structurecyclizationone pot synthesispriority journalproton nuclear magnetic resonancechemistrygreen chemistrysynthesis