Type: Letter

A combined computational/experimental study on HSA binding of two water-soluble Schiff base ligands derived from pyridine derivative and ethylendiamine

Journal: Journal of Biomolecular Structure and Dynamics (07391102)Year: 11 February 2019Volume: 37Issue: Pages: 641 - 648

Molaee H.Sahihi M.Moghadam M.^aMirkhani V.^aTangestaninejad S.^aMohammadpoor Baltork I.^aAmiri Rudbari H.^a

a :University of Isfahan - IRAN(IR) - Isfahan

DOI:10.1080/07391102.2018.1436091Language: English

Abstract

Author Keywords

fluorescence quenchingHSA bindingmolecular dockingmolecular dynamics simulationSchiff base ligandstabilizing agent

Other Keywords

Binding SitesEthylenediaminesHumansKineticsLigandsMolecular Docking SimulationMolecular Dynamics SimulationProtein BindingPyridinesSchiff BasesSerum Albumin, HumanSolubilitySpectrometry, FluorescenceThermodynamicsWateramineethylendiaminehuman serum albuminpyridine derivativeSchiff baseunclassified drugethylenediamine derivativeligandpyridineabsorption spectroscopybinding affinitychemical analysischemical interactionelemental analysisexperimental studyLetterligand bindingmolecular dockingmolecular dynamicspriority journalproton nuclear magnetic resonancerate constantspectrofluorometrysynthesisultraviolet spectroscopyX ray diffractionbinding sitechemistryhumanmetabolism