Type: Article

SO3H-functionalized MCM-41 as an efficient catalyst for the combinatorial synthesis of 1H-pyrazolo-[3,4-b]pyridines and spiro-pyrazolo-[3,4-b]pyridines

Journal: Journal Of The Iranian Chemical Society (1735207X)Year: 1 July 2017Volume: 14Issue: Pages: 1583 - 1589

Safaei S.Mohammadpoor Baltork I.^a Khosropour A.R.Moghadam M.^aTangestaninejad S.^aMirkhani V.^a

a :University of Isfahan - IRAN(IR) - Isfahan

DOI:10.1007/s13738-017-1099-8Language: English

Abstract

Sulfonic acid-functionalized (SO3H-functionalized) mesoporous MCM-41 catalyst was synthesized by anchoring 3-((3-(trimethoxysilyl)propyl)thio)propane-1-sulfonic acid onto MCM-41-type silica and characterized by FT-IR spectroscopy, elemental analysis and scanning electron microscopy (SEM) techniques. The catalyst was used for the efficient multi-component synthesis of 1H-pyrazolo-[3,4-b]pyridines and spiro-pyrazolo-[3,4-b]pyridines. Notably, the catalyst could be recycled and reused with negligible loss in activity over seven cycles. © 2017, Iranian Chemical Society.