Background
Type: Article

Synthesis of trans-1,3-diaryl-2-(5-methylisoxazol-3-yl)-2,3-dihydro-1H- naphtho[1,2-e][1,3]oxazines via bismuth(III)-catalyzed one-pot pseudo-four component reaction

Journal: Molecular Diversity (1573501X)Year: November 2012Volume: 16Issue: Pages: 727 - 735
DOI:10.1007/s11030-012-9408-8Language: English

Abstract

An expeditious, straightforward and efficient synthesis of diversely naphtho[1,2-e][1,3]oxazines via one-pot condensation reaction of β- naphthol, 3-Amino-5-methylisoxazole and arylaldehydes catalyzed by bismuth(III) trifluoromethanesulfonate is described. The reaction preferentially afforded 1,3-trans oxazines. © 2012 Springer Science+Business Media Dordrecht.