Type: Article

A green and selective synthesis of 2-aryloxazines and 2- aryltetrahydropyrimidines

Journal: Journal of Heterocyclic Chemistry (19435193)Year: 2011/03/01Volume: Issue: 2

Mohammadpoor Baltork I.^aMoghadam M.^aTangestaninejad S.^aMirkhani V.^a Eskandari Z.

a :University of Isfahan - IRAN(IR) - Isfahan

Abstract

An efficient method for the selective synthesis of 2-substituted oxazines and tetrahydropyrimidines by the reaction of arylnitriles with 3-amino-1-propanol and 1,3-diaminopropane in the presence of montmorillonite K-10 and KSF as inexpensive, environmentally benign, and reusable catalysts under classical heating conditions and microwave irradiation is reported. © 2010 HeteroCorporation.

Author Keywords

1,3 propanediamine2 (3 bromophenyl) 1,4,5,6 tetrahydropyrimidine2 (3 chlorophenyl) 1,4,5,6 tetrahydropyrimidine2 (3 cyanophenyl) 1,4,5,6 tetrahydropyrimidine2 (3 cyanophenyl) 5,6 dihydro 4h 1,3 oxazine2 (4 cyanophenyl) 1,4,5,6 tetrahydropyrimidine2 (4 cyanophenyl) 5,6 dihydro 4h 1,3 oxazine2 (4 pyridyl) 1,4,5,6 tetrahydropyrimidine2 aryloxazine derivative2 aryltetrahydropyrimidine derivative4 cyanopyridinemontmorilloniteoxazine derivativepyridine derivativepyrimidine derivativeunclassified drug