Background
Type: Article

[C6(MIm)2]2W10O32 catalyzed efficient one-pot pseudo-four component synthesis of AT-130 analogues under microwave irradiations

Journal: Journal Of The Iranian Chemical Society (1735207X)Year: 2014Volume: 11Issue: 5Pages: 1493 - 1501
Khosropour, Ahmad R. Mohammadpoor-Baltork, IrajSafaei, Shirin Mohammadpoor-Baltork, Iraj Rostami M. Rostami M. Khosropour A.R. Khosropour A.R.Mirkhani V.aMirkhani V.aMohammadpoor Baltork I.aMohammadpoor Baltork I.aMoghadam M.aMoghadam M.aTangestaninejad S.aTangestaninejad S.a
DOI:10.1007/s13738-014-0420-zLanguage: English

Abstract

Di[1,6-bis(3-methylimidazolium-1-yl)hexane] decatangstate ([C-6(MIm)(2)](2)W10O32) was found to be a novel, powerful and effective catalyst for the preparation of N-benzoylglycine carbamides as derivatives of AT-130 via one-pot multicomponent reaction performed under microwave irradiations. The products were obtained in high to excellent yields, thus providing a unique strategy to the large-scale synthesis of these compounds.


Author Keywords

AT-130AldehydesN-benzoylglycineAminesSolvent-freeMicrowave irradiationOrganic-inorganic hybrid polyoxometalatesOne-pot reactions

Other Keywords

CHRONIC HEPATITIS-BIONIC LIQUIDVIRUSPOLYOXOMETALATEDERIVATIVESEPOXIDATIONRESISTANCELAMIVUDINEINFECTIONALCOHOLS