Type: Article
One-pot, three-component condensation reaction in water: An efficient and improved procedure for the synthesis of pyran annulated heterocyclic systems
Journal: Synthetic Communications (15322432)Year: 2007/01/01Volume: 37Issue: 3Pages: 491 - 499
DOI:10.1080/00397910601039242Language: English
Abstract
Environmentally friendly three-component condensation reactions of an activated C-H acid, an aldehyde, and alkyl nitriles to afford the corresponding pyran annulated heterocyclic systems in water in good yields, avoiding the addition of any catalyst, are reported. Copyright © Taylor & Francis Group, LLC.
Author Keywords
1,3-dimethylbarbituric acid4-hydroxy-6-methylpyrone4-hydroxycoumarinPyran annulated heterocyclic systemThree-component reactionWater
Other Keywords
1,3 dimethyl 6 aminouracil1,3 dimethylbarbituric acid4 hydroxy 6 methylpyrone4 hydroxycoumarin5,5 dimethyl 1,3 cyclohexanedionealdehydealkyl groupbarbituric acid derivativeheterocyclic compoundnitrilepyranpyrone derivativeunclassified druguracil derivativewaterannulation reactionarticlecatalystchemical compositionpolymerizationsynthesis