Type: Article

Rapid and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by manganese (III) Schiff base complexes

Journal: Bioorganic and Medicinal Chemistry (09680896)Year: 2006/04/15Volume: Issue: 8

Nasr-Esfahani M.Moghadam M.^aTangestaninejad S.^aMirkhani V.^a Momeni A.R.

a :University of Isfahan - IRAN(IR) - Isfahan

DOI:10.1016/j.bmc.2005.11.051Language: English

Abstract

Rapid and efficient oxidation of Hantzsch 1,4-dihydropyridine with sodium periodate is reported. The Mn(III)-salophen/NaIO4 catalytic system converts 1,4-dihydropyridines to their corresponding pyridine derivatives at room temperature in a 1:1, CH3CN/H2O mixture. The ability of various Schiff base complexes in the oxidation of 1,4-dihydropyridine was also investigated. © 2005 Elsevier Ltd. All rights reserved.