Hashemi, S.M.,
Heidarpour, M.,
Eshaghian, A.,
Ansari, P.,
Hashemi, M.S.,
Yaghoobi, M.,
Barati, S. Publication Date: 2015
Iranian Journal Of Otorhinolaryngology (22517251)27(5)pp. 395-399
Introduction: Aneurysmal Bone cysts (ABC) are extremely rare in the head and neck region and even rarer in sinuses. ABC is a benign multicystic mass that is locally-destructive and rapidly expandable. Hemorrhagic fluid content (like in this case) and septated appearance are the characteristic feature of ABC. Established treatment options for ABCs include sclerotherapy, embolization, radiotherapy, simple curettage, surgical excision, or a combination of methods. Case Report: In this article, a 5 year-old boy with a recurrent nasal mass is presented. The patient was finally diagnosed with this rare entity: ABC of the paranasal sinuses. The patient was treated through complete surgical removal. Conclusion: ABC can be considered as a rare differential diagnosis of recurrent nasal hemorrhagic mass in a pediatric population. © 2015 Mashhad University of Medical Sciences. All rights reserved.
Publication Date: 2016
Language Related Research (23223081)7pp. 195-216
Hafez poems have complex and depth aspects. According to this feature everyone analysis the semantic structure of his poems differently. Structural study of Hafez narrative lyrics shows that not only different verses of lyric are not separate and disconnected but appear in a continuous and dynamic chain. Semantic integration of these lyrics and narrative structure of it provide the strong basis for semiotic study. For a better understanding of internal relations of narrative lyrics and its continuity and discontinuity, it is necessary to pay attention to the structure of narrative. The most widely used type of discourse in these poems is cognitive discourse, however sometimes the interaction between cognitive and emotional discourse is established in lyrics. In this way, Hafez destroys the common cognitions and suggest new and uncommon cognitions that are apparently against Islamic law and thereby criticizes the hypocrites of time and invites them to passion and drunkenness. In narrative lyrics, Cognition is associated with discourse discontinuity. The discourse of these lyric supports the integration of verses is established until the end of poem. So in this article we will survey the structure of Hafez Narrative lyrics and discourse discontinuity and continuity. © 2016, Tarbiat Modares University. All rights reserved.
Moafi, A.,
Rahgozar, S.,
Ghias, M.,
Ahar, E.V.,
Borumand, A.,
Sabbaghi, A.,
Sameti, A.,
Hashemi, S.M. Publication Date: 2011
International Journal Of Preventive Medicine (20088213)2(4)pp. 280-285
Objectives: Obesity and increased blood pressure are identified as risk factors for cardiac and pulmonary disorders. On the other hand, iron deficiency (another preventable disease) is common in adolescence and considered as associated with health impairment. The present study evaluates body mass index (BMI) and its association with blood pressure and hematological indices in freshman students entering the University of Isfahan in 2009. Methods: All the 1675 students who entered the University of Isfahan in September 2009 were examined. Height, weight, BMI, blood pressure, hemoglobin (Hb) and red blood cell (RBC) indices of these students were measured. The prevalence of high blood pressure, its association with BMI and the relation between BMI and anemia, iron deficiency and educational achievement were assessed. Results: All participants, including 514 males and 1161 females, went under clinical observations. The average age was 20.7 ± 3.8. year Among the students, 18.2% of males and 20% of females were underweight. High systolic blood pressure was more common in the students with BMI > 25 kg/m2 (p < 0.001). Anemia was seen in 8.7% of females. In males, however, a relation between anemia frequency and BMI < 18.5 kg/m2 was more distinct (p = 0.002). There was no association between anemia and students' average test scores. Conclusions: High incidence of abnormal BMI in the study population, and its association with systolic blood pressure indicate the importance of nutritional guidelines and counseling programs for freshman students. On the other hand, high incidence of anemia in this population ascertains the necessity of anemia screening programs before academic studies.
Taghian, E.,
Abtahi, S.H.,
Mohammadi, A.,
Hashemi, S.M.,
Ahmadikia, K.,
Dolatabadi, S.,
Mohammadi, R. Publication Date: 2023
Journal Of Research In Medical Sciences (17357136)28(1)pp. 12-12
Background: In natural conditions, inhaled fungi are considered a part of the microflora of nasal cavities and sinuses. However, subsequent to the protracted use of corticosteroids and antibacterial agents, suppression of the immune system by chemotherapy, and poor ventilation, these fungi can become pathogens. Fungal colonization in the nose and paranasal sinuses is a prevalent medical issue in immunocompetent and immunosuppressed patients. In this study, we aimed to categorize fungal rhinosinusitis (FRS) among immunocompetent and immunosuppressed patients and identified the etiologic agents of disease by molecular methods. Materials and Methods: A total of 74 cases were evaluated for FRS. Functional endoscopic sinus surgery was performed for sampling. The clinical samples were examined by direct microscopy with potassium hydroxide 20% and subcultured on Sabouraud Dextrose Agar with chloramphenicol. Polymerase chain reaction sequencing was applied to identify causative agents. Results: Thirty-three patients (44.6%) had FRS. Principal predisposing factors were antibiotic consumption (n = 31, 93.9%), corticosteroid therapy (n = 22, 66.6%), and diabetes mellitus (n = 21, 63.6%). Eyesore (n = 22, 66.6%), proptosis (n = 16, 48.5%), and headache (n = 15, 45.4%) were the most common clinical manifestations among patients. Rhizopus oryzae (n = 15, 45.4%) and Aspergillus flavus (n = 10, 30.3%) were the most prevalent fungal species. Conclusion: Diagnosis and classification of FRS are crucial, and a lack of early precise diagnosis can lead to a delay in any surgical or medical management. Since there are a variety of treatments for FRS, accurate identification of etiologic agents should be performed based on phenotypic and molecular methods. © 2023 Journal of Research in Medical Sciences.
Mohammadi, A.,
Hashemi, S.M.,
Abtahi, S.H.,
Lajevardi, S.,
Kianipour, S.,
Mohammadi, R. Publication Date: 2017
Journal Of Research In Medical Sciences (17357136)22(2)
Background: Fungal sinusitis is increasing worldwide in the past two decades. It is divided into two types including invasive and noninvasive. Noninvasive types contain allergic fungal sinusitis (AFS) and fungus ball. AFS is a hypersensitivity reaction to fungal allergens in the mucosa of the sinonasal tract in atopic individuals. The fungus ball is a different type of noninvasive fungal rhinosinusitis which is delineated as an accumulation of debris and fungal elements inside a paranasal sinus. Fungal sinusitis caused by various fungi such as Aspergillus species, Penicillium, Mucor, Rhizopus, and phaeohyphomycetes. The aim of the present study is to identify fungal species isolated from noninvasive fungal sinusitis by molecular methods. Materials and Methods: During 2015–2016, a total of 100 suspected patients were examined for fungal sinusitis. Functional endoscopic sinus surgery was performed using the Messerklinger technique. Clinical samples were identified by phenotypic and molecular methods. Polymerase chain reaction (PCR) sequencing of ITS1-5.8S-ITS2 region and PCR-restriction fragment length polymorphism with MspI restriction enzyme was performed for molecular identification of molds and yeasts, respectively. Results: Twenty-seven out of 100 suspected cases (27%) had fungal sinusitis. Nasal congestion (59%) and headache (19%) were the most common clinical signs among patients. Fifteen patients (55.5%) were male and 12 patients (44.5%) were female. Aspergillus flavus was the most prevalent fungal species (26%), followed by Penicillium chrysogenum (18.5%) and Candida glabrata species complex (15%). Conclusion: Since clinical manifestations, computed tomography scan, endoscopy, and histopathological findings are very nonspecific in AFS and fungus ball; therefore, molecular investigations are compulsory for precise identification of etiologic agents and appropriate management of these fungal infections. © 2017 Journal of Research in Medical Sciences.
Publication Date: 2017
Research in Contemporary World Literature/ Pazhuhesh-e Zabanha-ye Khareji (25887092)22(2)pp. 615-639
Different theories of western intellectuals about language and literature have made provided opportunities for new analysis of literary texts and language. One literary schools developed in the twentyth century is post-structuralism. Post-structuralists consider a sign in new ways. Julia Krista is one of Post- Structuralists whose ideas about literary texts caught attentions. Because of complexity and being blended with philosophy, her ideas are rarely used in Persian literature. Some parts of her theories deal with symbolism and semiotics in language. In her belief, language cannot be only signs or symbols and is a combination of both. As a result each one of them modify the other and the meaning is a product of their combination. This paper attempted to analyze symbolism and semiotics in the poem Ghesseye Shahre Sangestan (the story of stone city) of Akhavan which is one of the most prominent work of contemporary literature and to provide new interpretation for it. It can also serve as a sample to help understand the meaning of unreadable texts. © 2018, Faculty of Foreign Languages, University of Tehran. All rights reserved.
Hashemi, S.M.,
Berjis, N.,
Eshaghian, A.,
Nejadnic, M.,
Samani, A.F. Publication Date: 2015
Iranian Journal Of Otorhinolaryngology (22517251)27(80)pp. 213-217
Introduction: Dacryocystorhinostomy (DCR), a popular surgical procedure, has been performed using an endoscopic approach over recent years. Excellent anatomical knowledge is required for this endoscopic surgical approach. This study was performed in order to better evaluate the anatomical features of the lacrimal apparatus from cadavers in the Isfahan forensic center as a sample of the Iranian population. Materials and Methods: DCR was performed using a standard method on 26 cadaver eyes from the forensic center of Isfahan. The lacrimal sac was exposed completely, then the anatomical features of the lacrimal sac and canaliculus were measured using a specified ruler. Results: A total of 26 male cadaveric eyes were used, of which four (16.7%) were probably non-Caucasian. Two (8%) of the eyes needed septoplasty, one (4%) needed uncinectomy, and none needed turbinoplasty. Four (16%) lacrimal sacs were anterior to axilla, one (4%) was posterior and 20 (80%) were at the level of the axilla of the middle turbinate. The mean difference of distance from the nasal sill to the anterior edge of the lacrimal sac (from its mid-height) was 39.04 (±4.92) mm. The mean difference of distance from the nasal sill to the posterior edge of the lacrimal sac (from its mid-height) was 45.50 (±4.47) mm. The mean of width and length of the lacrimal sac was 7.54 (±1.44) mm and 13.16 (±5.37) mm, respectively. The mean difference of distance from the anterior edge of the lacrimal sac to the posterior edge of the uncinate process was 14.06 (±3.00) mm, while the mean difference of distance from the anterior nasal spine to the anterior edge of the lacrimal sac (from its mid-height) was 37.20 (±5.37) mm. The mean height of the fundus was 3.26 (±1.09) mm. The mean difference of distance from the superior punctum to the fundus was 12.70 (±1.45) mm, and from the inferior punctum to the fundus was 11.10 (±2.02) mm. Conclusion: Given the differences between the various studies conducted in order to evaluate the position of the lacrimal sac, studies such as this can help to better identify the position of lacrimal sac during surgery based on ethnic differences. In addition, these studies can help novice surgeons to better navigate in a surgical scenario.
Publication Date: 2017
Journal Of Research In Medical Sciences (17357136)22(1)
Background: This study was designed to determine the prevalence of concomitant anatomic variation of paranasal sinuses in patients with antrochoanal polyp (ACP). Materials and Methods: Among patients referred by their clinicians for standard computed tomography scan of paranasal sinuses septal deviation, concha bullosa, and retention cyst were evaluated in both patients with ACP as well as in a control group. Results: Of the 17 patients with ACP, fifteen patients (88.2%) had septal deviation and two patients (11.8%) had concha bullosa. None of the patients with ACP had retention cyst or hypertrophic turbinate. Of the 78 patients in control group, twenty‑nine (37.2%) had septal deviation, six (7.7%) had concha bullosa, seven (8.9%) had retention cyst, and one (1.2%) had hypertrophic turbinate. Septal deviation in patients with ACP has higher incidence (P < 0.001). Conclusion: This study showed that septal deviation is an anatomic variation which is significantly concomitant with ACP. Larger studies are needed to show the role of other anatomic variations in patients with ACP. © 2017 Journal of Research in Medical Sciences.
Publication Date: 2013
Allergology International (14401592)62(2)pp. 245-249
Background: There are few reports on the effects of intranasal Botulinum Toxin-A (BTX-A) as a treatment of allergic rhinitis (AR). In this study, we compared the efficacy of intranasal BTX-A to cetirizine in the treatment of AR. Methods: Fifty AR patients at the age of 26.2 ± 9.1 years (64% females), were recruited to the trial according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Participants randomly received either intranasal injection of BTX-A (75 IU Dyspor® or cetirizine (10 mg/day). Symptoms (based on the ARIA) and side effects were assessed every two weeks for two months. Quality of life was evaluated before and after the study using the Rhinasthma questionnaire. Results: Total symptom severity score of patients significantly decreased (P < 0.001) and quality of life signifi-cantly improved (P < 0.001) at the same level in both groups. Side effects included nasal dryness (4%) and epistaxis (4%) in the BTX-A group. In the cetirizine group 44% sleepiness and 4% blurred vision was reported. Conclusions: Nasal injection of BTX-A shows the same therapeutic effects as cetirizine in the management of AR. Since BTX is expensive, we do not suggest it in the first line of treatment for AR. However, BTX-A is a potential treatment for patients who are resistant or not compliant to the routine medications of AR. Further studies are required to investigate implications and limitations of BTX-A in the treatment of AR. © 2013 Japanese Society of Allergology.
Publication Date: 2017
International Journal Of Preventive Medicine (20088213)8
Background: Tinnitus is the perception of noise or ringing without external acoustic stimulants which affects almost 10% of general population. Many therapies have been recommended including diet modifications, herbal remedies, and chemical drugs. Most common utilized drugs for tinnitus are melatonin and antidepressants such as sertraline which have been proven in different studies. In this study, we aimed to compare the efficacy of melatonin and sertraline in treating tinnitus for the first time. Methods: In this clinical trial, 70 patients with tinnitus according to inclusion and exclusion criteria were included and randomly divided into two groups: melatonin group, taking melatonin 3 mg once daily and sertraline group taking sertraline 50 mg once daily, all treating for 3 months. Before and after treatments, every patient received Tinnitus Handicap Inventory (THI) questionnaire and severity of tinnitus was assessed, and data analysis was performed. Results: Before treatments, the mean of THI score for melatonin and sertraline groups were 45.02 ± 17.67 and 44.85 ± 20.57, respectively. There was no significant difference between both groups THI score (P = 0.23). After 3 months, the mean of THI scores for melatonin and sertraline groups were 30.29 ± 19.62 and 36.96 ± 25.03, respectively which the mean of THI scores in two groups was decreased significantly (P < 0.01, for‑both). In addition, indicated the significant decline in THI score of melatonin group who were under treatments with melatonin 3 mg once daily (P = 0.02). Conclusions: Here in this clinical trial, we demonstrated that both melatonin and sertraline are efficient in treating tinnitus, but the usage of melatonin 3 mg once daily is more effective. © 2017 International Journal of Preventive Medicine.
Rogha, M.,
Hashemi, S.M.,
Mokhtarinejad, F.,
Eshaghian, A.,
Dadgostar, A. Publication Date: 2014
Iranian Journal Of Otorhinolaryngology (22517251)26(74)pp. 7-12
Introduction: Cholesteatoma is traditionally diagnosed by otoscopic examination and treated by surgery. The necessity for imaging in an uncomplicated case is controversial. This study was planned to investigate the usefulness of a preoperative high-resolution computed tomography (HRCT) scan in depicting the status of middle ear structures in the presence of cholesteatoma dna also to compare the correspondence between pre- and intraoperative CT findings in patients with cholesteatoma. Materials and Methods: This prospective descriptive study was performed from January 2009 to May 2011 in 36 patients with cholesteatoma who were referred to the Kashani and Al-Zahra Clinics of Otolaryngology. Preoperative high-resolution temporal bone CT scans (axial and coronal views) were carried out and compared with intraoperative findings. Results: Evaluation of 36 patients and their CT scans revealed excellent correlation for sigmoid plate erosion, widening of aditus, and erosion of scutum; good correlation for erosion of malleus and tegmen; moderate correlation for lateral canal fistula (LCF) and erosion of mastoid air cells; and poor correlation for facial nerve dehiscence (FND), incus, and stapes erosion. Conclusion: A preoperative CT scan may be helpful in relation to diagnosis and decision making for surgery in cases of cholesteatoma and ossicular erosion. The CT scan can accurately predict the extent of disease and is helpful for detection of lateral canal fistula, erosions of dural plate, and ossicular erosions. However it is not able to distinguish between cholesteatoma and mucosal disease, facial nerve dehiscency, incus, and stapes erosion.
Publication Date: 2013
Language Related Research (23223081)4(2)pp. 27-54
One of the stages in the contemporary linguistics, based on which the linguists recognize a special position for speaker, is the “discourse analysis”. In this innovative linguistic perspective, the individual indicator, which influence on producing the texts, constitutes a new area in pragmalinguistic researches. Though we can pursue the history of acquaintance of linguistics with deixis in the rhetorical tradition of Islam, where the term appears by means of struggling, which arises from the process between grammar and rhetoric. Islamic grammarians are interested into internal context (co-text) & ask if there is a cohesion between the propositional members of the text and its external context (context of situation). Whereas, the rhetoricians study about the illocutionary force(s) of the utterances through corresponding this force with the context of situation. But among these scientists, there are others who synthesize between co-text & context simultaneously. They respect the deviations in grammatical principles in order to achieve the illocutionary or force(s) of utterances. This article argues some deixis in Ney-Nameh, such as personal pronouns, demonstratives, spatial-temporal indicators & expansion-contraction in discourse to evaluate the importance of speaker’s function in the above-mentioned discourse. In fact, this article would reply to this question that if by means of the deixis, we can go out of utterances’ level to appreciate the illocutionary forces of a total text and evaluate the correspondence of co-text and context. © 2013, Tarbiat Modares University. All rights reserved.
Publication Date: 2011
Journal Of Research In Medical Sciences (17357136)16(1)pp. 74-78
BACKGROUND: Recurrence of nasal polyposis following surgical intervention is very common. Antifungal therapy has been an appealing alternative to reduce its recurrence and severity. Early studies showed definite positive response, but recent studies have raised doubts about its efficacy in treatment of polyposis. METHODS: This prospective case-control clinical trial was conducted on 50 patients suffering from nasal polyposis in Isfahan university of medical sciences. All patients underwent functional endoscopic sinus surgery. CT scanning of paranasal sinuses was done preoperatively and 6 months postoperatively to stage the disease. Patients were assigned to two groups: amphotericine B group were instructed to irrigate the nasal cavity with a solution of amphotericine B, while the normal saline group used the physiologic normal saline for 6 months. RESULTS: 68% of patients in Normal saline and 84% of cases in amphotericine B group reported history of allergies. In amphotericine B group, stage of the disease improved in 84% of patients and remained unchanged in the rest. In normal saline group, imaging stage improved in 22 patients and remained unchanged in 3. The two cohorts were compared for reduction in imaging stage and no significant difference was found between them. CONCLUSIONS: This study showed no benefits for topical amphotericin B solution over normal saline. It might be better to retreat to the traditional normal saline nasal douching following functional endoscopic sinus surgery in the treatment of polyposis.
Salek, M.,
Hashemipour, M.,
Hashemi, S.M.,
Hajrahimi, M.,
Sadeghi, S.,
Farajzadegan, Z.,
Hovsepian, S.,
Hadian, R. Publication Date: 2007
Journal of Isfahan Medical School (10277595)25(87)pp. 53-59
Background: Congenital hypothyroidism (CH) has a considerably high prevalence in our country, and without early treatment, it would lead to irreversible sequelae like hearing impairment. This study was aimed to investigate the prevalence of hearing loss in children with CH in comparison with healthy children. Methods: This case-control study was conducted in two groups of children; the case group consisted of 94 children with CH aged more than 4 months under follow up in Isfahan endocrine research center; the control group included 450 healthy infants underwent routine neonatal hearing screening in a private hospital. First, Otto Acoustic Emission (OAE) test was performed, and in the case of being abnormal, then auditory brain stem response (ABR) test was conducted. Children with abnormal ABR were considered to have hearing impairment. Findings: The prevalence of hearing impairment was not significantly different between children with CH and controls (3.2% vs. 0.2%, respectively; p>0.05). The mean age of beginning the treatment for CH was not significantly different between children with or without hearing impairment (13.6±8.3 vs. 16.4±8.05 days, respectively; p>0.05).The mean T4 and TSH was not significantly different between children with CH with and without hearing impairment (5.6±4.2 mg/dl and 133.7±80.3 MIU/l vs. 6.2±3.7 mg/dl and 116.5±92.1 MIU/l, respectively; p>0.05). Conclusion: We did not document any difference in the prevalence of hearing impairment in children with CH and controls; this finding might be because of limited number of subjects studied and the short duration of follow up. There was no difference neither between the age of beginning the treatment for CH and hearing impairment, nor between the mean T4 and TSH at birth and hearing impairment. Hearing loss has no relationship with age at treatment onset and primary T4 and TSH level at diagnoses. © 2007, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Barati, B.,
Omrani, M.R.,
Okhovat, A.,
Kelishadi, R.,
Hashemi, S.M.,
Hassanzadeh, A.,
Abtah, M.,
Omidifar, N.,
Okhovat, H. Publication Date: 2011
Journal Of Research In Medical Sciences (17357136)16(4)pp. 509-515
Background: Antimicrobials treatment of Otitis media (OM) reduces some complications, but some of chronic complications, and specially otitis media with effusion (OME), seem to increase. Theoretically the usage of nasal corticosteroid sprays may prevent this problem by reducing the local inflammation around the eustachian tube. So, this study aimed to evaluate the role of nasal corticosteroid spray as an adjuvant for the treatment of OME. Methods: In a randomized, prospective clinical trial, 2 groups of 46 subjects who had OME were recruited. A questionnaire containing patients' characters, history, complaints, otologic examinations, and the report of tympanometries was filled for all before and after treatment. We administered a period of amoxicillin and a decongestant for both group and nasal beclomethasone spray only for case group. Results: Thirty five of cases (76.1%) and 22 (47.8%) of controls had an improvement in their symptoms or the quality of hearing (p = 0.005). Partial remission was the most common finding in 52.2% of the patients in the case group but for control group there was no change (p = 0.024). The higher improvement in the tympanic retraction in the case group was significant (p < 0.05). A significant better tympanometric result has showed in the treatment of left ear in the patients of the case group (p = 0.038) but not for right ear (p = 0.136). Conclusions: We concluded that the administration of nasal beclomethasone spray as an adjuvant for the treatment of OME not only improved the results treatment but also increased the resolution of symptoms and the patients' quality of hearing.
Publication Date: 2023
Advanced Biomedical Research (22779175)12(1)pp. 202-202
Background: Tonsillectomy, one of the most common otolaryngology surgeries, often results in postoperative complications such as pain and bleeding. Currently, there is no consensus on postoperative pain management. This study aimed to determine the efficacy of oral prednisolone on postoperative pain after tonsillectomy with sutures. Materials and Methods: This pilot, double-blind, randomized clinical trial was conducted at two tertiary care centers affiliated with Isfahan University of Medical Sciences. Patients who underwent tonsillectomy with sutures were included. Participants were randomly divided into experimental and control groups. In the experimental group, patients received oral prednisolone in addition to acetaminophen; in the control group, patients received acetaminophen and a placebo. Post-operative pain was evaluated by a visual analog scale daily for ten days. Results: Initially, 60 patients were enrolled in the study; however, four were excluded due to non-attendance at follow-up visits. The groups were similar in terms of age and sex (both P values >0.05). In the study, postoperative pain from 1 st day to the 10 th day was lower in the experimental group than in the control group (P value <0.05). Conclusion: Numerous studies have been conducted on the effect of intravenous corticosteroids on this pain. However, there is no consensus on the analgesic role of oral corticosteroids for post-tonsillectomy pain. The present study showed that oral prednisolone is effective on post-operative pain compared to a placebo. © 2023 Advanced Biomedical Research.
Hashemi, S.M.,
Sakhi, N.,
Ghazavi, H.,
Bolourinejad, P.,
Kheirabadi, G. Publication Date: 2020
European Journal of Plastic Surgery (0930343X)43(2)pp. 153-158
Abstract: Background: Psychological functioning of rhinoplasty must be evaluated in the community of Iran as the most prevalent center of rhinoplasty worldwide. Making a realistic public view about rhinoplasty psychological outcomes is necessary. In the present study, quality of life, anxiety, depression, and self-esteem alteration in rhinoplasty patients among the Iranian population were assessed. Methods: This is an observational trial study conducted on 41 patients who underwent rhinoplasty in 2017–2018. The Persian version of standard questionnaires “World Health Organization Quality of Life (WHOQOL-26),” “Hospital Anxiety and Depressive Scale (HADS),” and “Eysenck Self-Esteem Questionnaire” were used for this aim. Therefore, questionnaires were filled pre and within 6 months postoperatively and then compared. Demographics including age, gender, marital status, and educational level association with the mentioned factors were assessed as well. Results: The results revealed that rhinoplasty brought significant improvements in all aspects of QOL, including physical (P value = 0.011), psychological (P value = 0.002), relationships (P value = 0.019), environment (P value = 0.032), and general health (P value = 0.005). Depression (P value = 0.010) and self-esteem (P value = 0.004) scores change significantly in a positive manner as well. Anxiety improvement was the least (6.8%) with no significant change (P value = 0.334). None of the demographics including age, gender, marital status, and educational level showed association with psychological indices (P value > 0.05) except for age association with relationships domain of WHOQOL that was significantly higher among those younger than 30 years old (P value = 0.040). Conclusions: Rhinoplasty can improve most of the psychological indices in the Iranian population, regardless of the candidate’s gender, marriage status, educational level, or age group. Level of evidence: Level II, therapeutic study. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
Hashemi, S.M.,
Rogha, M.,
Miralahi, S.,
Nakhaei, A.,
Khodami, A.R. Publication Date: 2009
Journal of Isfahan Medical School (10277595)27(98)
Background: Intratympanic steroid injection is an effective method in treatment of sudden sensorineural hearing loss in cases resisted to systemic therapy. The purpose of this study was to determine the efficacy of intratympanic injection. Methods: This case-series study was carried out on fifteen patients with sudden sensorineural hearing loss that had failed systemic therapy. Audiometric evaluation (PTA) performed before and after treatment and intratympanic dexametasone injection performed and the amount of improvement evaluated. Data Analysis was done using SPSS11. Findings: In male patients, 33.3% partial and 33.3% complete improvement and in female patients, 18.6% partial and 50% complete improvement was reported. In cases with lower degrees of hearing loss, total improvement was 66.7%; also earlier time of treatment had better results. Conclusion: Intratympanic injection of steroid is one effective modality in treatment of sudden sensorineural hearing loss in cases with no response to standard systemic therapy. It can improve the hearing level of patients while its complication rate is low and as degree of hearing loss increases the results decrease earlier treatment have a better results. © 2009, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Publication Date: 2024
Language Related Research (23223081)14(6)pp. 339-371
This article seeks to explicate the interpretive model of symbolic expressions, termed "the evolutionary-oriented pattern", relying on the semiotic foundations of Charles Sanders Peirce, an American pragmatist philosopher and semiotician. Inspired by the ideas of Robert Neville (1996), who initiated the adaptation of Peirce's framework to the realm of religious language, the article adopts a descriptive-critical approach. In the first section, it delves into defining the position of metaphor among various types of signs according to Peirce's classification. Subsequently, it discusses the structure and mechanism of interpreting symbolic expressions within the framework of two semiotic processes, and finally, it elucidates the formation of the semantic network of symbols-metaphors by combining both aforementioned processes. In this article, for the first time, two distinct processes in Peircean semiosis, namely, transcendental and non- transcendental processes, have been identified. The roles of each in creating a semantic chain among signs on one hand and between a sign and its interpretant on the other hand have been elucidated. Among the other achievements of this research are the introduction of conceptual frameworks such as interpretive aspect, semantic context, and the referential scope, each playing a role in the systematic interpretation of a sign. © 2024, Tarbiat Modares University. All rights reserved.
Okhovvat, A.R.,
Karim, M.,
Hashemi, S.M.,
Hashemi, S.M.,
Berjis, N.,
Amiridavan, M. Publication Date: 2010
Journal of Isfahan Medical School (10277595)27(103)
Background: We report the diagnosis, treatment and follow–up process of 22 cases of fungal sinusitis. Methods: This case- series study was carried out on 22 patients with fungal sinusitis that had treatment of endoscopy and antifungal drug. Past medical history, pathology, CT scan findings and treatment of patients were evaluated. Data analysis was done using SPSS. Findings: Twelve male (57%) and 10 female (43%) patients with the age of 16-73 years were a ssessed. Mucormycosis was seen in 18 (82%) and Aspergilosis in 4 (18%) patients. Diabetic mellitus (71%), chronic renal failure (CRF) (14.3%), and leukemia (9.6%) were reported as the most common underlying diseases. Maxillary and etmoid sinuses were the site of involvement. The most common sign was unilateral periorbital edema and proptosis (95%), and the most common symptom was unilateral change of visual acuity and cheek sensation (95%). All the patients had endoscopy surgery and treated with amphotricine B or ithraconazole and ceftrinaxone, metronidazole and vancomycine. Death was reported in 5 patients (22%) and renewed functional endoscopic sinus surgery (FESS) in 1 (4.8%). Conclusion: Functional endoscopic sinus surgery with amphotncine B or ithraconazole and follow-up are effective for fungal sinusitis. © 2010, Isfahan University of Medical Sciences(IUMS). All rights reserved.
Hashemipour, M.,
Hovsepian, S.,
Hashemi, S.M.,
Amini, M.,
Kelishadi, R.,
Sadeghi, S. Publication Date: 2012
Iranian Journal Of Pediatrics (20082150)22(1)pp. 92-96
Objective: Thyroid hormone is necessary for normal development of the auditory system. The aim of this study was to investigate the rate of hearing impairment in congenitally hypothyroid (CH) patients, and its relation with factors such as CH severity and age at starting treatment, during CH screening program in Isfahan. Methods: Hearing acuity was assessed in two groups of children with (94 patients aged 4 months - 3 years) and without CH (450), between 2000-2006. Otoacostic emission (OAE) was performed by a two step method. After two tests without OAE signals bilaterally, they were referred for auditory brainstem response (ABR) test. Subjects with both OAE and ABR abnormal test results were considered to have hearing problem. Obtained data was compared in case and control group and also CH patients with and without hearing impairment. Findings: Three (3.2%) of patients and 1 of control group (0.2%) were diagnosed with sensorineural hearing loss. The rate of hearing loss was not different significantly in two studied groups (P>0.05). There was no difference between age of starting treatment and first T4 and TSH level in CH patients with and without hearing loss (P>0.05). CH neonates with hearing impairment had thyroid dyshormonogenesis according to the follow up results. Conclusion: The rate of hearing loss was low among our studied CH patients. It may be due to proper management of CH patients. In view of the fact that all CH neonates were dyshormonogentic and considering the relation between certain gene mutations and hearing impairment in CH patients, further studies with larger sample size, with regard to different etiologies of CH should be investigated to indicate the possible gene mutations related to hearing loss in CH. © 2012 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, All rights reserved.
Rogha, M.,
Berjis, N.,
Lajevardi, S.,
Alamdaran, M.,
Hashemi, S.M. Publication Date: 2019
International Journal Of Preventive Medicine (20088213)10(1)
Background: Tongue cancer is the most common malignancy of the mouth. In recent decades, reported tongue cancer incidence and mortality rates have increased all over the world while survival has not improved that sometimes is related to mutation, especially in gene P53 (such R249, R248 mutations). Hence, this study aimed to identification of R249 mutation in P53 gene of tumor tissue in tongue cancer. Methods: In a cross-sectional study, 48 patients with squamous cell carcinoma (SCC) of tongue were selected, and mutation of R249 was investigated in sample of tumors. In addition, demographic data and medical history of patients were determined and registered in a collected data form. Finally added data were entered to computer and analyzed by SPSS software. Results: Polymerase-chain reaction test done on tissue samples from cancer patients showed that in a studied sample of 48 patients, 4 of them (8.3%) had R249 mutation. After selecting the codon 249 as a hotspot in oral cancer, forward and reverse primers for amplification of exon 7 were obtained from the articles. Conclusions: Considering the findings of our study, R249 mutation in P53 gene in patients with SCC is relatively high. Age and alcohol consumption were factors affecting incidence of the mutation. It is necessary to take an early treatment with a single lesion of tongue to prevent severe disease and prevent disease in patient's family with screening test and prevent cancer in future with gene therapy. © 2019 Wolters Kluwer Medknow Publications. All rights reserved.
Publication Date: 2017
Language Related Research (23223081)8(8)pp. 293-320
Language is considered as the basic material in research on literature & mysticism. For the linguistics can enable researchers to achieve functional approaches. Although the presupposition was accounted in the past issue of the more basic subjects in domain of linguistics and newer approaches have shown little interest about this phenomenon by logical analysis, but reflect on some of these issues can assist in the analysis of invisible aspects of the meaning which was usually neglected in generative grammar. The research methodology is descriptive – analytic. It should consider the presuppositions as the specific kinds of conversational implicatures that, particularly, by means of the connectors of the discourse, such as conjunctions (but, so, in addition, etc) transfer the cognitive value of the propositions to the audience. This paper tries to respond to this question that how the presuppositions can figure the evolution of mystical principles in Sama' through its association with the requirements of ontological, epistemological and cultural context of the subject. © 2017, Tarbiat Modares University. All rights reserved.
Sonbolestan s.m., ,
Barzegar f., ,
Jamshidi m., M.,
Hashemi, S.M.,
Honarmand a., Publication Date: 2008
Tehran University Medical Journal (17357322)66(6)pp. 402-407
Background: Post-tonsillectomy pain is often severe and usually prevents patients from routine eating and drinking. A new option for reducing postoperative pain is "preemptive analgesia", the pre-, intra-or post-operative administration of analgesic agents. Ketamine, an N-methyl D-aspartate receptor antagonist, has recently received attention for this aim. Herein, we study the effect of submucosal injection of ketamine in the tonsillar bed for the reduction of post-tonsillectomy pain. Methods: In this double-blind clinical trial, three groups of patients underwent infiltration of 0.5mg/kg ketamine, 1mg/kg ketamine or normal saline in their tonsillar bed. Age, sex and weight of patients, duration of surgery, systolic and diastolic blood pressure (before and after surgery), volume of blood loss, reoccurrence of bleeding, time to initiation of oral intake, nausea, vomiting, pain score and dysphasia were recorded in information sheet. Data analysis was performed by one-way ANOVA and chi squared tests, with significance at a P value of <0.5. Results: There is no significant difference between the three groups with regard to age, sex, weight, duration of surgery, blood pressure (before surgery), volume of blood loss, nausea and vomiting. However, for the ketamine groups, pain score, dysphasia, need for opioid administration and time to initiation of oral intake is significantly lower (P<0.00). Reoccurrence of bleeding was observed in one patient in the lower-dose ketamine group, which is not statistically significant. The effectiveness of the two doses of ketamine is similar, with no statistical difference between the two groups (P=0.84). Conclusions: This study demonstrated that a submucosal injection of ketamine into the tonsillar bed preoperatively is a safe option for reducing post-tonsillectomy pain, dysphasia, need for opioid and time to initiation of oral intake, without increasing the risk of excessive bleeding, reoccurrence of bleeding, nausea and vomiting. © 2008, Tehran University of Medical Sciences. All rights reserved.
Publication Date: 2005
Journal Of Research In Medical Sciences (17357136)10(3)pp. 167-171
Background: The purpose of this study was microbiology of chronic resistant rhino sinusitis with or without nasal polyp in patients undergoing functional endoscopic sinus surgery and antimicrobial resistance testing. Patients and methods: In a cross-sectional study during December 2000 to June 2002, 94 CRS patients with or without nasal polyp were sampled through FESS for microbiology culture and In-vivo antimicrobial resistance was tested in both groups. Results: In CRS group with polyps (42 patients), the most common isolated organisms were Staph. coagulase-negative (26.2%), Staph. areous (23.8%), E-Coli (16.7%), Klebsiella (14.3%) and Enterobacter (7.1%). In CRS group without polyps (52 patients), the most common isolated organisms were Staph. coagulase-negative (25%), Staph. areous (11.5%), Klebsiella (9.6%), E-Coli (7.7%) and Strep. Non-group A (7.7%). Normal flora grew in 5 cultures (9.6%). In only one culture of CRS group without polyp, Pseudomonas was isolated. No resistance was reported from gram-positive bacteria against vancomycin and gram-negative rods were sensitive to ciprofloxacin, ceftriaxon and ceftizoxim. Conclusion: Despite of some previous studies, the most common micro- organisms in the cultures of CRS cases, regardless of having nasal polyps or not, were Staph. coagulase-negative, Staph. aureus and gram-negative rods, respectively. The incidence of GNRs in CRS group with nasal polyps is higher which may lead to special antibiotic therapy in them. Increasing In Vivo resistance of these bacteria to antibiotics is problematic and the routine old antimicrobial therapy may not be effective enough to control these pathogens and avoid surgical therapy. However, In Vivo evaluations are recommended to reveal a better interpretation.
Publication Date: 2024
Teosofi: Jurnal Tasawuf dan Pemikiran Islam (20887957)14(2)pp. 221-239
The scholarship on the last days (dkhir al-zamdn) has predominantly centered around religious and historical texts, leaving out the rich mystical sources within Shia culture. This study aims to fill this gap by investigating Islamic mysticism from the second to the tenth century AH, written in Persian and Arabic. By delving into these mystical writings, this research intends to shed light on the transformative impact of discussions in the last days and the way mystics approached this subject. The overlooked evolution of these writings remains significant for grasping the continued relevance of discussions on the last days in contemporary Shia society and other religions. The research suggests that discussions surrounding the concept of the last days have been a source of considerable debate among mystics dating back to the first mystical tradition, with these interpretations often incorporating elements from several religions, becoming more intricate in subsequent periods, and influencing Shia culture today. © 2024. The authors.
