Type:

Efficient synthesis of 1,5-benzodiazepines catalyzed by silica supported 12-tungstophosphoric acid

Journal: Catalysis Communications (15667367)Year: 20 September 2008Volume: 9Issue: Pages: 2496 - 2502

Abdollahi-Alibeik M.Mohammadpoor Baltork I.^a Zaghaghi Z. Yousefi B.H.

a :University of Isfahan - IRAN(IR) - Isfahan

DOI:10.1016/j.catcom.2008.07.004Language: English

Abstract

Silica supported 12-tungstophosphoric acid efficiently catalyzes the reaction of o-phenylenediamine with ketones under solvent free condition to afford the corresponding 1,5-benzodiazepines in good to excellent yields. The catalyst can be recovered by simple filtration and reused. © 2008 Elsevier B.V. All rights reserved.