One-pot, three-component condensation reaction in water: An efficient and improved procedure for the synthesis of pyran annulated heterocyclic systems

Abstract

Environmentally friendly three-component condensation reactions of an activated C-H acid, an aldehyde, and alkyl nitriles to afford the corresponding pyran annulated heterocyclic systems in water in good yields, avoiding the addition of any catalyst, are reported. Copyright © Taylor & Francis Group, LLC.