Type: Article
Synthesis of a structure containing three N-fused heterocycles with very high bond-forming through a one-pot reaction
Journal: Tetrahedron (00404020)Year: 2020/02/14Volume: 76Issue: 7
Alizadeh-Kouzehrash M.Rahmati A.a
DOI:10.1016/j.tet.2020.130923Language: English
Abstract
Some new N-fused heterocyclic compounds have been simply synthesized via a mild and efficient one-pot two-step four-component reaction between hydrazine hydrate, various 3-oxoalkanonitriles, 2-phthaldehydic acid and different CH-acids in ethanol, in the presence of 4-toluenesulfonic acid as catalyst. A large number of bonds (9 bonds) are formed during the transformation. © 2020 Elsevier Ltd