Articles
Publication Date: 2026
Entrepreneurship Education and Pedagogy (25151274)9(1)pp. 3-20
Entrepreneurship has traditionally been regarded as a skillset best suited for adults. However, recent research indicates that adolescents also possess entrepreneurial traits and may even exhibit higher levels of these skills than many adults. The purpose of this study was to develop and validate the Perceived Entrepreneurship Skills Scale (PESS) in adolescents. The study aimed to develop and validate the PESS in three phases. The first phase involved item generation and analysis, which resulted in the retention of 40 items (n = 100 participants). In the second phase, exploratory factor analysis was conducted, revealing 8 factors that emerged from the analysis (n = 233). In the third phase, the confirmatory factor analysis and validation of PESS were investigated with a sample of urban students in Iran, ranging from grade 7 to 12, with a total of 292 participants. The tool demonstrated good discriminant validity, indicating that it is an effective measure of perceived entrepreneurship skills in adolescents, and adequate convergent validity. The PESS has significant implications for researchers, school counselors and psychologists, policymakers, and stakeholders. © The Author(s) 2024
Publication Date: 2025
Cancer Communications (25233548)(5)pp. 529-571
Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential. However, the development of cancer vaccines is hindered by several challenges, including low stability, inadequate immune response activation, and the immunosuppressive tumor microenvironment, which limit their efficacy. Recent progress in various fields, such as click chemistry, nanotechnology, exosome engineering, and neoantigen design, offer innovative solutions to these challenges. These achievements have led to the emergence of smart vaccine platforms (SVPs), which integrate protective carriers for messenger ribonucleic acid (mRNA) with functionalization strategies to optimize targeted delivery. Click chemistry further enhances SVP performance by improving the encapsulation of mRNA antigens and facilitating their precise delivery to target cells. This review highlights the latest developments in SVP technologies for cancer therapy, exploring both their opportunities and challenges in advancing these transformative approaches. © 2025 The Author(s). Cancer Communications published by John Wiley & Sons Australia, Ltd. on behalf of Sun Yat-sen University Cancer Center.
Publication Date: 2025
Pajouhan Scientific Journal (24236276)23(1)pp. 1-12
Background and Objectives: Wisdom is an emerging topic in education and psychology. The present study aimed to incorporate the principles and characteristics of wisdom into parenting programs and examine the effectiveness of wise parenting in social-emotional values and resilience among preschool children.Materials and Methods: This quasi-experimental study employed a pre-test and post-test design with experimental and control groups. The statistical population consisted of mothers of preschool children (ages 4-6) in Isfahan in 2023. Participants were selected through multistage cluster random sampling and randomly assigned to the experimental and control groups (15 mothers per group). The research instrument was a scale measuring social and emotional values and resilience in preschool children, completed by the mothers. The experimental group received ten 90-minute sessions of wise parenting training, while the control group received no intervention. Data were analyzed in SPSS software (version 23) using multivariate analysis of covariance (MANCOVA).Results: The results indicated that wise parenting training significantly improved children's social and emotional values and resilience (P<0.05). In the experimental group, the mean score increased from 55.26±13.45 in the pre-test to 99.26±9.85 in the post-test, whereas the control group showed no significant difference between the pre-test (70.13±23.41) and post-test (71.13±22.53) scores.Conclusion: As evidenced by the obtained results, wise parenting can enhance social-emotional values and resilience in preschool children. Therefore, it is recommended that wise parenting be integrated into parental education programs alongside other existing parenting approaches. © 2024. Pajouhan Scientific Journal.
Publication Date: 2025
Journal of Applied Psychological Research (22518126)16(1)pp. 15-26
The objective of the current investigation was to investigate the perceptions of wisdom held by Iranian gifted school instructors. In order to accomplish this objective, a descriptive phenomenological methodology was implemented. The statistical population of the research consisted of teachers from gifted schools in Isfahan in 2022. Purposive sampling was implemented to identify participants, and data acquisition was maintained until saturation was achieved. The study involved 21 teachers, with interviews lasting between 30 and 45 minutes. Eight of the instructors were male and thirteen were female. Interviews were conducted in-depth to facilitate a two-way dialogical exchange and obtain a comprehensive understanding of the teachers’ perspectives. The data derived from the interviews were analyzed using Clark and Brown's six-step model. Additionally, Lincoln and Guba’s four criteria were implemented to guarantee the credibility and validity of the investigation. The results indicated that the conceptualization of wisdom by gifted school teachers is characterized by three primary themes: cognitive and rational skills, communication and interpersonal skills, and compassion and concern for others. The results of this study suggest that teachers’ perceptions reflect certain aspects of wisdom, while others, as emphasized in the literature, are underemphasized. © The Author(s).
Background: Staphylococcus saprophyticus (S. saprophyticus) is the second most prevalent etiological agent of urinary tract infections (UTIs) in young women. However, there is a paucity of data regarding its bacteriophage (phage). Therefore, this study was conducted to isolate and identify new lytic phages from municipal wastewater with the objective of increasing knowledge about phages and their genomes. Methods: A total of 11 clinical isolates of S. saprophyticus and 30 wastewater samples were used to isolate three lytic phages (vB_SsapH-Golestan-100, vB_SsapH-Golestan101-M, and vB_SsapH-Golestan-105-M). The morphology, behavioral characteristics, and complete DNA genomes of these phages were analyzed. Results: The microscopic images of the phages revealed that the sizes of their heads and tail lengths fell within the ranges of 90–111 nm and 234–266 nm, respectively. All phages exhibited high adsorption rates (99.5% in 15 min) and burst sizes (150–210 PFU per infected cell), with a potential for a narrow host range. Genomic analysis of Staphylococcus phages indicated a size of 136,433 base pairs (bp) with a guanine-cytosine (GC) content of 33.7% and 192 open reading frames (ORFs) for vB_SsapH-Golestan-100, 144,081 bp with a GC content of 29.6% and 205 ORFs for vB_SsapH-Golestan101-M, and 142,199 bp with a GC content of 30.6% and 203 ORFs for vB_SsapH-Golestan-105-M. A bioinformatics analysis indicated that all three phages belong to the Twortvirinae subfamily of Herelleviridae. Among the three phages, vB_SsapH-Golestan-100 exhibited the least similarity to previously known phages, with less than 21% similarity with its closest counterparts in genomic databases. Conclusions: This study identified new phages that have the ability to destroy a broad range of S. saprophyticus isolates and may potentially be classified as a new genus and species within the Herelleviridae family in future studies. © The Author(s) 2025.
