Rahmanian M., Yaghoobpoor S., Deravi N., Poudineh M., Mirmohammadali S.N., Kashanizadeh M.G., Poopak A., Faridzadeh A., Erabi G., Amouei E., Falahatian M., Khani A., Sadatmadani S.-F., Noroozi, M., Firouzabadi F.D.
Publication Date: 2024
Neurology Asia (18236138)(1)pp. 145-155
Nonalcoholic fatty liver disease (NAFLD) refers to the uncontrolled accumulation of triglyceride (TG) in the liver when the person has no other liver disease etiologies. Among all causes of neuropathy, diabetic neuropathy is the most common one worldwide, and it causes notable morbidity and increases mortality. The prevalence of diabetic neuropathy and NAFLD has been demonstrated in few studies. This study aims to summarize existing data estimating peripheral diabetic neuropathy prevalence among sonographically detected NAFLD patients. We searched PubMed, Scopus, Web of Science, and Google scholar for articles in the English language up until October 2021 for the clinical trials of diabetic neuropathy in NAFLD patients and used the articles for a systematic review and meta-analysis. Seven studies (6,918 patients with type 2 diabetes mellitus (T2DM)) were involved. The prevalence of diabetic neuropathy among T2DM patients with ultrasound (US) detected-NAFLD was 0.48 (95% CI= 0.31-0.65, I2= 99.01%), however it was not significantly different from patients without NAFLD (OR=1.02, 95% CI= 0.89-1.17. p=0.748, I2=81.6%). The prevalence of diabetic neuropathy among T2DM patients with NAFLD is not significantly different from patients without NAFLD. © 2024, ASEAN Neurological Association. All rights reserved.
Gashmard R., Hasanpour E., Daman S., Amini P.H., Sefidi M.J.G., Ladani F.K., Bagherieh M., Nabizadeh M.
Publication Date: 2024
Revista Latinoamericana de Hipertension (18564550)(8)pp. 342-348
Introduction: Heart disease can have debilitating physical and mental consequences that can affect the care behavior of the elderly. The aim of study was the effect of a support program based on the psychosocial needs of the family on the family care burden of ischemic heart patients. Methods: Science Direct, Pub Med, Google Scholar, SID, MagIran databases were reviewed and electronic data were used to identify the psychosocial needs of the family on the burden of family care of heart patients. In the initial search, 824 articles were obtained, of which 379 duplicate articles were removed. Considering the inclusion and exclusion criteria, the number of articles was reduced to 445 articles. Finally, 10 articles were included in study. Results: A total of 824 articles were screened, which led to the selection of 11 studies that met the inclusion criteria and were included in study. Some studies defined caregivers as family caregivers. Five studies focused on life partners and caregivers of patients. Some studies generally defined caregivers as someone identified by the patient as a caregiver. Conclusion: Providing a training program about the different dimensions of support that family caregivers need reduces the perceived stress of family caregivers of cardiac patients. © 2024, Venezuelan Society of Pharmacology and Clinical and Therapeutic Pharmacology. All rights reserved.
Nouri H., Nasri R., Abtahi S.-H.
Publication Date: 2023
International Journal of Retina and Vitreous (20569920)(1)
Background: Optical coherence tomography angiography (OCTA) is an innovative technology providing visual and quantitative data on retinal microvasculature in a non-invasive manner. Main body: Due to variations in the technical specifications of different OCTA devices, there are significant inter-device differences in OCTA data, which can limit their comparability and generalizability. These variations can also result in a domain shift problem that may interfere with applicability of machine learning models on data obtained from different OCTA machines. One possible approach to address this issue may be unsupervised deep image-to-image translation leveraging systems such as Cycle-Consistent Generative Adversarial Networks (Cycle-GANs) and Denoising Diffusion Probabilistic Models (DDPMs). Through training on unpaired images from different device domains, Cycle-GANs and DDPMs may enable cross-domain translation of images. They have been successfully applied in various medical imaging tasks, including segmentation, denoising, and cross-modality image-to-image translation. In this commentary, we briefly describe how Cycle-GANs and DDPMs operate, and review the recent experiments with these models on medical and ocular imaging data. We then discuss the benefits of applying such techniques for inter-device translation of OCTA data and the potential challenges ahead. Conclusion: Retinal imaging technologies and deep learning-based domain adaptation techniques are rapidly evolving. We suggest exploring the potential of image-to-image translation methods in improving the comparability of OCTA data from different centers or devices. This may facilitate more efficient analysis of heterogeneous data and broader applicability of machine learning models trained on limited datasets in this field. © 2023, Brazilian Retina and Vitreous Society.
Shahin, K., Soleimani-delfan, A., He Z., Sansonetti P., Collard J.-M.
Publication Date: 2023
Gut Pathogens (17574749)(1)
The human gut bacteriome is believed to have pivotal influences on human health and disease while the particular roles associated with the gut phageome have not been fully characterized yet with few exceptions. It is argued that gut microbiota can have a potential role in autism spectrum disorders (ASD). The public microbiota database of ASD and typically developing (TD) Chinese individuals were analyzed for phage protein-coding units (pPCU) to find any link between the phageome and ASD. The gut phageome of ASD individuals showed a wider diversity and higher abundance compared to TD individuals. The ASD phageome was associated with a significant expansion of Caudoviricetes bacteriophages. Phages infecting Bacteroidaceae and prophages encoded within Faecalibacterium were more frequent in ASD than in TD individuals. The expansion and diversification of ASD phageome can influence the bacterial homeostasis by imposing pressure on the bacterial communities. In conclusion, the differences of phages community in in ASD and TD can be used as potential diagnosis biomarkers of ASD. Further investigations are needed to verify the role of gut phage communities in the pathogenesis of ASD. © 2023, BioMed Central Ltd., part of Springer Nature.
Mirabi E., Pishvaie M.R., Abbasian M.
Publication Date: 2013
Iranian Journal Of Chemistry And Chemical Engineering (10219986)(3)pp. 91-105
Fuel cells belong to an avant-garde technology family for a wide variety of applications including micro-power, transportation power, stationary power for buildings and other distributed generation applications. The first objective of this contribution is to find a suitable reduced model of a Solid Oxide Fuel Cell (SOFC). The derived reduced model is then used to design a state estimator. In the first step, the distributed model of the SOFC that is derived using the first principle balance equations is solved by the method of lines. Since this model is too complex and sluggish for real-time applications, a representation of this model with lower number of states and good accuracy is needed. Karhunen-Loève-Galerkin (KLG) procedure is used to develop such a reduced model.
Salamat Y., Moghadassi A., Illbeigi M., Eslamimanesh a., , Mohammadi A.H.
Publication Date: 2013
Journal of Energy Chemistry (2095-4956)(1)pp. 114-118
In this paper, the effect of adding different concentrations of kinetic inhibitors on the induction time of hydrogen sulfide hydrate formation in a reactor equipped with automatic adjustable temperature controller is studied. A novel method namely "sudden cooling" is used for performing the relevant measurements, in which the induction time of H2S hydrate in the presence/absence of PVP and L-tyrosine with different concentrations (100, 500, and 1000 ppm) is determined. As a result, PVP with the concentration of 1000 ppm in aqueous solution is detected as a more suitable material for increasing the induction time of H2S hydrate formation among the investigated kinetic hydrate inhibitors. © 2013, Dalian Institute of Chemical Physics, Chinese Academy of Sciences.
Seyfi S., Nikjoo A.H., Rezaei O., Siyamian A.
Publication Date: 2013
Tourismos (17908418)(2)pp. 289-299
The purpose of this paper is to explore the attitude and perception of local residents toward tourism impacts and development in Torqabeh, one of the most popular tourism resort located in northeast of Iran. Two hundred and fifty households were randomly chosen as a sample of study and data were collected and analyzed with quantitative methods. The results of analysis revealed that local residents generally expressed a positive attitude toward tourism development in Torqabeh. There was evidence that Tourism-related job, community involvement in making decisions about tourism development, community attachment and length of residence are significant determinants of perceived tourism impacts and development. Furthermore, the study reinforces the need for inclusion of local people during future preliminary process of tourism planning in area. © University of the Aegean.
Mirzabagherl D., Hajihashemi Sh., Yavarzadeh M.R., Sepehri H., Abaszadeh M., Mostafaiee M., Soltani A.
Publication Date: 2012
Ecology, Environment and Conservation (discontinued) (0971765X)(4)pp. 781-792
In the present study phylogenetic consepts of 49 species (76 sequence accessions) representing 42 species of Gracilaria , 3 species of Gracilariopsis and as outgroups 2 species of Hypnea , 1 species of Sarconema and 1 species of Soleria wereevaluated based on maximum parsimony and neighbor joining analysis of chloroplast-encoded rbcL and rbcS genes and rbcL-rbcS space region ( spacer ). The results identified Iranian Gracilaria species situate in 4 clades (5 species in Gracilaria sensu stricto and 2 species in Hydropontia). Molecular data confirmed accuracy of recognition of Gracilaria corticata, Gracilaria arcuata, Gracilaria salicornia and Gracilaria textorii. According to phylogenic analysis name of "Gracilaria armata" changed to "Gracilaria arcuata" and it is necessary to review the name of Gracilaria canaliculata, which is introduced from Iran. Upon the results, Iranian Gracilaria sp. is a close species to Gracilaria canaliculata. The molecular study on different population of Gracilaria corticata showed that despite of small difference in morphologic aspect, they are similar from molecular aspect and found in the monophyletic clade. Copyright © EM International.
Noruzi M., Zare, D., Khoshnevisan K., Davoodi D.
Publication Date: 2011
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy (13861425)(5)pp. 1461-1465
This study reports a green method for the synthesis of gold nanoparticles using the aqueous extract of rose petals. The effects of gold salt concentration, extract concentration and extract quantity were investigated on nanoparticles synthesis. Gold nanoparticles were characterized with different techniques such as UV-vis spectroscopy, FT-IR spectroscopy, X-ray diffraction, energy dispersive X-ray spectroscopy, dynamic light scattering and transmission electron microscopy. Transmission electron microscopy experiments showed that these nanoparticles are formed with various shapes. FT-IR spectroscopy revealed that gold nanoparticles were functionalized with biomolecules that have primary amine group (-NH 2), carbonyl group, -OH groups and other stabilizing functional groups. X-ray diffraction pattern showed high purity and face centered cubic structure of gold nanoparticles. Dynamic light scattering technique was used for particle size measurement, and it was found to be about 10 nm. The rate of the reaction was high and it was completed within 5 min. © 2011 Elsevier B.V. All rights reserved.
Ansari Y., Gerasim D., Mahdavinia M.
Publication Date: 2011
African Journal of Agricultural Research (1991637X)(15)pp. 3619-3622
Although agricultural credit is one of the important issues in agriculture, almost no organized study has been done on caring about the distribution and utilization to achieve the agricultural prosperity and economic growth. This analytic and descriptive study was conducted to explore, that factor affecting the efficiency of agricultural facilities from viewpoint of farmers and credit experts. To achieve the objectives of the study, the survey data were collected by an effective and reliable questionnaire designed to this study. Results indicated that the process of agricultural training, low age and higher education of farmer had a positive significance relationship with effectiveness of their earning facilities on the fields of profit, increasing productions employment, and satisfaction with farming. © 2011 Academic Journals.
Hosseini, S.R., Pouryayevali m.r.,
Publication Date: 2011
Nonlinear Analysis, Theory, Methods and Applications (0362546X)(12)pp. 3884-3895
In this paper, a notion of generalized gradient on Riemannian manifolds is considered and a subdifferential calculus related to this subdifferential is presented. A characterization of the tangent cone to a nonempty subset S of a Riemannian manifold M at a point x is obtained. Then, these results are applied to characterize epi-Lipschitz subsets of complete Riemannian manifolds. © 2011 Elsevier Ltd. All rights reserved.
Khoshnevisan K., Bordbar, A., Zare, D., Davoodi D., Noruzi M., Barkhi M., Tabatabaei, M.
Publication Date: 2011
Chemical Engineering Journal (1385-8947)(2)pp. 669-673
Cellulase on commercial superparamagnetic nanoparticles was characterized by DLS, and TEM methods in relation to their size and structure. The cellulase enzyme was bound via physical adsorption (ionic bound). FTIR spectroscopy confirmed the successful binding of cellulase (endoglucanase) onto the particle, and binding efficiency was determined at 95% using the Bradford method. The maximal enzyme activity was assessed using CMC as the substrate and was 0.1. unit (μmol/min. ml). The adsorption capacity of cellulase onto nanoparticles reached 31. mg/g. The stability of the immobilized enzyme increased in comparison with the free enzyme. Overall, this study showed that that the stability and activity of the cellulase were enhanced via physical adsorption to the magnetic nanoparticles. This suggested that immobilized enzyme on magnetic beads could be used in an interesting range of application allowing both using in broader temperature and pH ranges, facilitating long-term storage, while permitting magnetic recovery of the enzyme for reuse or purification of the product. © 2011 Elsevier B.V.
Heravi M.R.P., Loghmani-khouzani, H., Sadeghi, M.M.M., Zendehdel, M., Jackson, R.F.W., Adams, H.
Publication Date: 2009
X-ray Structure Analysis Online (18833578)(4)pp. 43-44
The title compound, 2-(4-methoxybenzylthio)-1-phenylethanone, was synthesized and structurally characterized by single-crystal X-ray diffraction. The space group was Pna21 with the following unit-cell parameters: a = 7.5424(4)Å, b = 11.9347(6)Å, c = 15.2506(7)Å, V = 1372.80(12)Å3 and Z = 4. The final R value was R1 = 0.0274 for 1499 measured reflections. 2009 © The Japan Society for Analytical Chemistry.
Asgary S., Moshtaghian, J., Hosseini M., Siadat H.
Publication Date: 2008
Pakistan Journal Of Pharmaceutical Sciences (1011601X)(4)pp. 460-464
Alfalfa (Medicago sativa) is a leguminous plant with high contents of phytoestrogen and saponin which are both useful in preventing cardiovascular disorders. This study was designed to evaluate the preventive effect of dietary alfalfa on the development and the progression of atherosclerosis in hyperlipidemic rabbits. Twenty male rabbits were obtained and kept under standard conditions. After 2 weeks of accommodation to the new place, the animals were semi-randomly distributed into four groups of five each. Animals in Group 1 received basic diet and the ones in Group 2 received the same diet to which 1% cholesterol was added. Groups 3 and 4 received similar diets as Groups 1 and 2 respectively, but supplemented with alfalfa. Each of the four groups was fed with its respected diet for a period of 12 weeks. Fasting blood samples were collected from all animals at the beginning and at the end of the study and blood factors were measured. At the end of the study samples from the right and the left coronary arteries as well as the aorta were collected from all animals for pathological evaluations. Though dietary alfalfa decreased total cholesterol, LDL and triglyceride and this effect was not significant, but dietary alfalfa significantly increased HDL. The formation of fatty streaks in the aorta, the right and the left coronary arteries were significantly reduced under the influence of dietary alfalfa. The indication that dietary alfalfa may have preventive effects on the progression of fatty streak formation calls for more studies to clarify the mechanisms of the effect.
Faghihian h., H., Mohammadi M.H.
Publication Date: 2008
Iranian Journal Of Chemistry And Chemical Engineering (10219986)(4)pp. 115-118
Nitrate is an anion of major importance particularly in biological areas. Excessive amounts in water supplies indicate pollution from sewage or agricultural effluents. The effects of excessive quantities of nitrate in water are well known. In this research structural modification of natural clinoptilolite by isomorphic substitution was performed. Isomorphously substituted zeolite was prepared under melting conditions from natural clinoptilolite. It was characterized by XRD, XRF, DIG and SEM techniques. The characterization process revealed that product is different from AlPo. Ion exchange property of the modified product was studied for NO3, NO2, and F' ion. The uptake ofF' was higher than those of NO 3, and NO2,. Anion exchange isotherms were constructed for NO3, and discussed. The ion exchange chromatography and neutron activation technique were used to study the extent of the exchange.
Pakravan, G., Foroughmand, A.M., Peymani, M., Ghaedi, K., Hashemi, M., Hajjari M., Nasr-esfahani, M.H.
Publication Date: 2018
Cell Death and Disease (20414889)(7)
Doxorubicin (Dox) is a widely used powerful chemotherapeutic component for cancer treatment. However, its clinical application has been hampered due to doxorubicin-induced cardiomyopathy upon the cessation of chemotherapy. Previous studies revealed that PPARγ plays a crucial protective role in cardiomyocytes. Modulation of miRNA expression is an applicable approach for prohibition of toxicity induction. Therefore, the aim of present study is uprising of PPARγ transcript levels via manipulation of miRNAs to limit Dox-induced cardiotoxicity in mESCs-derived cardiac cells, as in vitro model cell to provide a simple direct approach for further clinical therapies. Based on bioinformatics data mining, eventually miR-130a was selected to target PPARγ. This miRNA is highly expressed in heart. The expression of miR-130a increases sharply upon Dox treatment while specific antagomiR-130a reverses Dox-induced reduced expression of PPARγ, cellular apoptosis, and inflammation. Our data strongly suggest that antagomiR-130a limits Dox-induced cellular toxicity via PPARγ upregulation and may have clinical relevance to limit in vivo Dox toxicity. © 2018 The Author(s).
Borzooeian Z., Taslim M.E., Ghasemi O., Rezvani S., Borzooeian G., Nourbakhsh A.
Publication Date: 2018
PLoS ONE (19326203)(6)
Parametric separation of carbon nanotubes, especially based on their length is a challenge for a number of nano-tech researchers. We demonstrate a method to combine bio-conjugation, SDS-PAGE, and silver staining in order to separate carbon nanotubes on the basis of length. Egg-white lysozyme, conjugated covalently onto the single-walled carbon nanotubes surfaces using carbodiimide method. The proposed conjugation of a biomolecule onto the carbon nanotubes surfaces is a novel idea and a significant step forward for creating an indicator for length-based carbon nanotubes separation. The conjugation step was followed by SDS-PAGE and the nanotube fragments were precisely visualized using silver staining. This high precision, inexpensive, rapid and simple separation method obviates the need for centrifugation, additional chemical analyses, and expensive spectroscopic techniques such as Raman spectroscopy to visualize carbon nanotube bands. In this method, we measured the length of nanotubes using different image analysis techniques which is based on a simplified hydrodynamic model. The method has high precision and resolution and is effective in separating the nanotubes by length which would be a valuable quality control tool for the manufacture of carbon nanotubes of specific lengths in bulk quantities. To this end, we were also able to measure the carbon nanotubes of different length, produced from different sonication time intervals. © 2018 Borzooeian et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Publication Date: 2018
Journal of Applied Remote Sensing (19313195)12(3)
Hoz-e-Sultan playa is one of the lowest points in the center of Iran, and its size and shape rely on the amount of inlet and outlet discharged water in different seasons of the year. The temperature fluctuations are the significant variations in the surface of the playa that increases the maximum salinity and saline layer level. Therefore, the present study aimed to investigate the spatial-temporal changes and salinity rate obtained from 11 sedimentary cores in the study area by principal component analysis, Normalized Difference Salinity Index (NDSI), and Land Surface Temperature (LST) method. The results indicated that the level of playa decreased about 33.598 km2 during 26 years. The spatial changes occurred in the eastern margin in the south of playa. Finally, a significant relationship was observed between the SI and the real salinity, and the NDSI and LST also increase the salinity rate related to temperature decrease. © 2018 The Authors.
Hossein, H.H.S., Zarrabi, A., Zarepour, A.
Publication Date: 2017
Journal of Babol University of Medical Sciences (15614107)(6)pp. 64-70
BACKGROUND AND OBJECTIVE: Considering the increasing number of patients with cancer and the relative ineffectiveness of existing treatments, finding a modern technique for cancer treatment has been one of the major topics of research in recent decades. The present study aims to load curcumin anticancer drug on targeted iron oxide nanoparticles. METHODS: In this laboratory research, iron oxide nanoparticles were synthesized using polyol method. Then, they were coated with polyglycerol as a polymeric coating through ring - opening polymerization method. Folic acid (with three weight ratios of 2, 25 and 50%) was used to target the system constructed for specific penetration into the cancer cells. The experiments of loading the drug were performed with three weight ratios of 0.5, 1 and 2 µg nanoparticles on coated and targeted nanoparticles. Then, drug release rate was measured under in vitro conditions. Finally, MTT Assay was used to analyze cell toxicity of the loaded drug. FINDINGS: Results indicated successful construction of 20 nm nanoparticles. The maximum rate of drug loading into the system was about 88 and 82% for non-targeted nanoparticles and targeted nanoparticles, respectively, while increased targeting had adverse effects on drug loading. Moreover, the loaded drug had a more successful therapeutic effect compared with the free drug. CONCLUSION: Results of the study demonstrated that the constructed nanoparticles have the necessary efficiency to act as a system for transferring anticancer drug. © 2017, Babol University of Medical Sciences. All rights reserved.
Sengupta B., Sahihi, M., Dehkhodaei, M., Kelly D., Arany I.
Publication Date: 2017
PLoS ONE (19326203)(6)
Plant flavonoids are well known as antioxidants against oxidative stress induced by exposure to external pollutants. Nicotine (NIC) is one of those agents which increases renal oxidative stress, an important factor in the pathogenesis of renal epithelial injury in smokers. Although several studies had been conducted on flavonoids and oxidative stress, the mechanism of the protective pathways are not fully understood. Here, we present studies on antioxidant properties of two mono-hydroxyflavone isomers, 3-hydroxyflanove (3HF)-and 7-hydroxyflavone (7HF), against nicotine-associated oxidative stress and injury in cultured renal proximal tubule cells and correlate their antioxidant properties with their chemical structure. Our data clearly demonstrates, for the first time, that while both 3HF and 7HF protect renal cells from NIC-associated cytotoxicity, the mechanism of their action is different: 3HF elicits protective activity via the PKA/CREB/MnSOD pathway while 7HF does so via the ERK/Nrf2/HO-1 pathway. Molecular docking and dynamics simulations with two major signaling pathway proteins showed significant differences in the binding energies of 3HF (-5.67 and -7.39 kcal.mol-1) compared to 7HF (-5.41 and -8.55 kcal.mol-1) in the matrices of CREB and Keap1-Nrf2 proteins respectively, which corroborate with the observed differences in their protective properties in the renal cells. The implications of this novel explorative study is likely to promote the understanding of the mechanisms of the antioxidative functions of different flavones. © 2017 Sengupta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Zonoubi R., Eslami-rasekh, A., Tavakoli, M.
Publication Date: 2017
System (0346251X)pp. 1-12
Teachers' efficacy beliefs exert a significant influence on their practice and their students' learning. This study investigates the contribution of two six-month Professional Learning Community (PLC) interventions to 10 English as a Foreign Language (EFL) novice and experienced teachers' self-efficacy. The data were collected through pre and post-interviews with the participants, their reflective journals, and recordings of the PLC meetings. The findings suggest that the experienced teachers' self-efficacy improved in terms of employing innovative instructional strategies and language proficiency. An increase was also observed in the novice teachers’ self-efficacy for classroom management, their autonomy, and their perceived language proficiency. Finally, the participants in both groups developed a stronger sense of professional community membership as reflected in their focus on their collective efficacy toward the end of the PLCs. © 2017
Peimanifard Z., Rashid-nadimi, S.
Publication Date: 2017
Electrochemistry Communications (13882481)pp. 37-40
A concept for light-powered visual detection of glucose is developed. The detection mechanism is based on pairing a photo-active anode with an electrochromic counter electrode. The photoelectrochemical reaction changes the oxidation state of the analyte, leading to a change in the color of the electrochromic material, which makes visual detection possible. All of the electrical charge required to change the color of the electrochromic material is supplied by the photoelectrochemical reaction powered by visible light, so no conventional energy source is required. The proposed system consists of hematite modified with nickel hydroxide (Ni(OH)2) as the photoanode, and Prussian blue deposited on a fluorine-doped tin oxide electrode as the electrochromic cathode. Under illumination, photo-oxidation of glucose at the photoanode is followed by reduction of Prussian blue to Prussian white at the cathode. The presence of glucose can therefore be detected visually as decolorization of Prussian blue occurs. © 2017 Elsevier B.V.
Motayyeb S., Fakhri S.A., Varshosaz m., M., Pirasteh S.
Publication Date: 2022
CTIT workshop proceedings series (16821750)(B1-2022)pp. 389-398
In recent years, Unmanned Aerial Vehicles (UAVs) have become popular tools in mapping applications. In such applications, the image motion, bad lighting effects, and poor texture all directly affect the quality of the derived tie points, which in turn imposes constraints on image extraction and may lead to a low accuracy point cloud. This paper proposes a contrast enhancement technique to improve the accuracy of a photogrammetric model created using UAV images. The luminance component (Y) in the YIQ color space is normalized using the sigmoid function, and the low contrast images are enhanced using the Contrast-Limited Adaptive Histogram Equalization (CLAHE) on the luminosity component. To evaluate the proposed method, three-dimensional models were created using images acquired by the Phantom 4 Pro UAV in three distinct places and at altitudes of 20, 40, 60, 80, and 90 meters. The results showed that enhancing the contrast of images increased the number of tie points and reduced reprojection error by approximately 10%. It also improved the resolution of the digital elevation model by approximately 2cm/pixel while greatly improving the texture and quality with respect to that developed using the original images. © 2022 S. Motayyeb et al.
Shahin, K., Soleimani-delfan, A., Zhang, L., Hedayatkhah, A., Mansoorianfar, M., Bao, H., Barazandeh, M., Enteshari J., Wang, R.
Publication Date: 2022
Microbiology Resource Announcements (2576098X)(6)
Here, we report the genome of phage SAP012, which was isolated against Salmonella enterica serovar Typhimurium. The SAP012 genome is 59,618 bp, with a G1C content of 56.2% and with no antibiotic resistance or virulence genes, and is quite similar at the nucleotide level to a number of previously sequenced Salmonella phage genomes, e.g., GenBank accession numbers KM366098.1 and KC139515.1. Copyright © 2022 Shahin et al.
Mehrasa, M., Doostmohammadi, M., Forootanfar H., Amini S., Davari, N., Salehi, H., Amirpour, N.
Publication Date: 2022
Materials Today Communications (23524928)
Stem cell therapy is a promising approach involving the application of pluripotent cells for the treatment of a vast variety of diseases. There are several reports on designing and development of methods for suitable differentiation of stem cells to neural lineage. In this study, we investigated the potency of align and random poly(lactic-co-glycolic acid) (PLGA) nano-fibers containing mesoporous silica nanoparticles (MSNPs) in differentiation of human adipose derived stem cells (hADSCs) into anterior neuroectodermal cells. The expression level of four anterior neuroectodermal markers including OTX2, SIX3, PAX6 and RAX was quantified for better understanding of the effect of scaffolds on cell differentiation. According to the obtained results, it seems that align PLGA/MSNPs scaffolds are suitable for anterior neuroectodermal induction of hADSCs. Considering the absence of chemical agents for cell differentiation and with respect to the surprisingly high level of all four markers in the aligned fibers, using these scaffolds is introduced as a safe, cheap and powerful method for easy differentiation of hADSCs into anterior neuroectodermal cells. © 2022
Brusseau V., Tauveron I., Bagheri, R., Ugbolue U.C., Magnon V., Navel V., Bouillon-Minois J.-B., Dutheil, F.
Publication Date: 2022
PLoS ONE (19326203)(6-Jun)
Introduction Hypothyroidism may be associated with changes in the autonomic regulation of the cardiovascular system, which may have clinical implications. Objective To conduct a systematic review and meta-analysis on the impact of hypothyroidism on HRV. Materials and methods PubMed, Cochrane, Embase and Google Scholar were searched until 20 August 2021 for articles reporting HRV parameters in untreated hypothyroidism and healthy controls. Random-effects meta-analysis were stratified by degree of hypothyroidism for each HRV parameters: RR intervals (or normal to normal-NN intervals), SDNN (standard deviation of RR intervals), RMSSD (square root of the mean difference of successive RR intervals), pNN50 (percentage of RR intervals with >50ms variation), total power (TP), LFnu (low-frequency normalized unit), HFnu (high-frequency), VLF (very low frequency), and LF/HF ratio. Results We included 17 studies with 11438 patients: 1163 hypothyroid patients and 10275 healthy controls. There was a decrease in SDNN (effect size = -1.27, 95% CI -1.72 to -0.83), RMSSD (-1.66, -2.32 to -1.00), pNN50 (-1.41, -1.98 to -0.84), TP (-1.55, -2.1 to -1.00), HFnu (-1.21, -1.78 to -0.63) with an increase in LFnu (1.14, 0.63 to 1.66) and LF/HF ratio (1.26, 0.71 to 1.81) (p <0.001). HRV alteration increased with severity of hypothyroidism. Conclusions Hypothyroidism is associated with a decreased HRV, that may be explained by molecular mechanisms involving catecholamines and by the effect of TSH on HRV. The increased sympathetic and decreased parasympathetic activity may have clinical implications. Copyright: © 2022 Brusseau et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
