Rahmanian M., Yaghoobpoor S., Deravi N., Poudineh M., Mirmohammadali S.N., Kashanizadeh M.G., Poopak A., Faridzadeh A., Erabi G., Amouei E., Falahatian M., Khani A., Sadatmadani S.-F., Noroozi, M., Firouzabadi F.D.
Publication Date: 2024
Neurology Asia (18236138)(1)pp. 145-155
Nonalcoholic fatty liver disease (NAFLD) refers to the uncontrolled accumulation of triglyceride (TG) in the liver when the person has no other liver disease etiologies. Among all causes of neuropathy, diabetic neuropathy is the most common one worldwide, and it causes notable morbidity and increases mortality. The prevalence of diabetic neuropathy and NAFLD has been demonstrated in few studies. This study aims to summarize existing data estimating peripheral diabetic neuropathy prevalence among sonographically detected NAFLD patients. We searched PubMed, Scopus, Web of Science, and Google scholar for articles in the English language up until October 2021 for the clinical trials of diabetic neuropathy in NAFLD patients and used the articles for a systematic review and meta-analysis. Seven studies (6,918 patients with type 2 diabetes mellitus (T2DM)) were involved. The prevalence of diabetic neuropathy among T2DM patients with ultrasound (US) detected-NAFLD was 0.48 (95% CI= 0.31-0.65, I2= 99.01%), however it was not significantly different from patients without NAFLD (OR=1.02, 95% CI= 0.89-1.17. p=0.748, I2=81.6%). The prevalence of diabetic neuropathy among T2DM patients with NAFLD is not significantly different from patients without NAFLD. © 2024, ASEAN Neurological Association. All rights reserved.
Gashmard R., Hasanpour E., Daman S., Amini P.H., Sefidi M.J.G., Ladani F.K., Bagherieh M., Nabizadeh M.
Publication Date: 2024
Revista Latinoamericana de Hipertension (18564550)(8)pp. 342-348
Introduction: Heart disease can have debilitating physical and mental consequences that can affect the care behavior of the elderly. The aim of study was the effect of a support program based on the psychosocial needs of the family on the family care burden of ischemic heart patients. Methods: Science Direct, Pub Med, Google Scholar, SID, MagIran databases were reviewed and electronic data were used to identify the psychosocial needs of the family on the burden of family care of heart patients. In the initial search, 824 articles were obtained, of which 379 duplicate articles were removed. Considering the inclusion and exclusion criteria, the number of articles was reduced to 445 articles. Finally, 10 articles were included in study. Results: A total of 824 articles were screened, which led to the selection of 11 studies that met the inclusion criteria and were included in study. Some studies defined caregivers as family caregivers. Five studies focused on life partners and caregivers of patients. Some studies generally defined caregivers as someone identified by the patient as a caregiver. Conclusion: Providing a training program about the different dimensions of support that family caregivers need reduces the perceived stress of family caregivers of cardiac patients. © 2024, Venezuelan Society of Pharmacology and Clinical and Therapeutic Pharmacology. All rights reserved.
Nouri H., Nasri R., Abtahi S.-H.
Publication Date: 2023
International Journal of Retina and Vitreous (20569920)(1)
Background: Optical coherence tomography angiography (OCTA) is an innovative technology providing visual and quantitative data on retinal microvasculature in a non-invasive manner. Main body: Due to variations in the technical specifications of different OCTA devices, there are significant inter-device differences in OCTA data, which can limit their comparability and generalizability. These variations can also result in a domain shift problem that may interfere with applicability of machine learning models on data obtained from different OCTA machines. One possible approach to address this issue may be unsupervised deep image-to-image translation leveraging systems such as Cycle-Consistent Generative Adversarial Networks (Cycle-GANs) and Denoising Diffusion Probabilistic Models (DDPMs). Through training on unpaired images from different device domains, Cycle-GANs and DDPMs may enable cross-domain translation of images. They have been successfully applied in various medical imaging tasks, including segmentation, denoising, and cross-modality image-to-image translation. In this commentary, we briefly describe how Cycle-GANs and DDPMs operate, and review the recent experiments with these models on medical and ocular imaging data. We then discuss the benefits of applying such techniques for inter-device translation of OCTA data and the potential challenges ahead. Conclusion: Retinal imaging technologies and deep learning-based domain adaptation techniques are rapidly evolving. We suggest exploring the potential of image-to-image translation methods in improving the comparability of OCTA data from different centers or devices. This may facilitate more efficient analysis of heterogeneous data and broader applicability of machine learning models trained on limited datasets in this field. © 2023, Brazilian Retina and Vitreous Society.
Shahin, K., Soleimani-delfan, A., He Z., Sansonetti P., Collard J.-M.
Publication Date: 2023
Gut Pathogens (17574749)(1)
The human gut bacteriome is believed to have pivotal influences on human health and disease while the particular roles associated with the gut phageome have not been fully characterized yet with few exceptions. It is argued that gut microbiota can have a potential role in autism spectrum disorders (ASD). The public microbiota database of ASD and typically developing (TD) Chinese individuals were analyzed for phage protein-coding units (pPCU) to find any link between the phageome and ASD. The gut phageome of ASD individuals showed a wider diversity and higher abundance compared to TD individuals. The ASD phageome was associated with a significant expansion of Caudoviricetes bacteriophages. Phages infecting Bacteroidaceae and prophages encoded within Faecalibacterium were more frequent in ASD than in TD individuals. The expansion and diversification of ASD phageome can influence the bacterial homeostasis by imposing pressure on the bacterial communities. In conclusion, the differences of phages community in in ASD and TD can be used as potential diagnosis biomarkers of ASD. Further investigations are needed to verify the role of gut phage communities in the pathogenesis of ASD. © 2023, BioMed Central Ltd., part of Springer Nature.
Mirabi E., Pishvaie M.R., Abbasian M.
Publication Date: 2013
Iranian Journal Of Chemistry And Chemical Engineering (10219986)(3)pp. 91-105
Fuel cells belong to an avant-garde technology family for a wide variety of applications including micro-power, transportation power, stationary power for buildings and other distributed generation applications. The first objective of this contribution is to find a suitable reduced model of a Solid Oxide Fuel Cell (SOFC). The derived reduced model is then used to design a state estimator. In the first step, the distributed model of the SOFC that is derived using the first principle balance equations is solved by the method of lines. Since this model is too complex and sluggish for real-time applications, a representation of this model with lower number of states and good accuracy is needed. Karhunen-Loève-Galerkin (KLG) procedure is used to develop such a reduced model.
Salamat Y., Moghadassi A., Illbeigi M., Eslamimanesh a., , Mohammadi A.H.
Publication Date: 2013
Journal of Energy Chemistry (2095-4956)(1)pp. 114-118
In this paper, the effect of adding different concentrations of kinetic inhibitors on the induction time of hydrogen sulfide hydrate formation in a reactor equipped with automatic adjustable temperature controller is studied. A novel method namely "sudden cooling" is used for performing the relevant measurements, in which the induction time of H2S hydrate in the presence/absence of PVP and L-tyrosine with different concentrations (100, 500, and 1000 ppm) is determined. As a result, PVP with the concentration of 1000 ppm in aqueous solution is detected as a more suitable material for increasing the induction time of H2S hydrate formation among the investigated kinetic hydrate inhibitors. © 2013, Dalian Institute of Chemical Physics, Chinese Academy of Sciences.
Seyfi S., Nikjoo A.H., Rezaei O., Siyamian A.
Publication Date: 2013
Tourismos (17908418)(2)pp. 289-299
The purpose of this paper is to explore the attitude and perception of local residents toward tourism impacts and development in Torqabeh, one of the most popular tourism resort located in northeast of Iran. Two hundred and fifty households were randomly chosen as a sample of study and data were collected and analyzed with quantitative methods. The results of analysis revealed that local residents generally expressed a positive attitude toward tourism development in Torqabeh. There was evidence that Tourism-related job, community involvement in making decisions about tourism development, community attachment and length of residence are significant determinants of perceived tourism impacts and development. Furthermore, the study reinforces the need for inclusion of local people during future preliminary process of tourism planning in area. © University of the Aegean.
Mirzabagherl D., Hajihashemi Sh., Yavarzadeh M.R., Sepehri H., Abaszadeh M., Mostafaiee M., Soltani A.
Publication Date: 2012
Ecology, Environment and Conservation (discontinued) (0971765X)(4)pp. 781-792
In the present study phylogenetic consepts of 49 species (76 sequence accessions) representing 42 species of Gracilaria , 3 species of Gracilariopsis and as outgroups 2 species of Hypnea , 1 species of Sarconema and 1 species of Soleria wereevaluated based on maximum parsimony and neighbor joining analysis of chloroplast-encoded rbcL and rbcS genes and rbcL-rbcS space region ( spacer ). The results identified Iranian Gracilaria species situate in 4 clades (5 species in Gracilaria sensu stricto and 2 species in Hydropontia). Molecular data confirmed accuracy of recognition of Gracilaria corticata, Gracilaria arcuata, Gracilaria salicornia and Gracilaria textorii. According to phylogenic analysis name of "Gracilaria armata" changed to "Gracilaria arcuata" and it is necessary to review the name of Gracilaria canaliculata, which is introduced from Iran. Upon the results, Iranian Gracilaria sp. is a close species to Gracilaria canaliculata. The molecular study on different population of Gracilaria corticata showed that despite of small difference in morphologic aspect, they are similar from molecular aspect and found in the monophyletic clade. Copyright © EM International.
Noruzi M., Zare, D., Khoshnevisan K., Davoodi D.
Publication Date: 2011
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy (13861425)(5)pp. 1461-1465
This study reports a green method for the synthesis of gold nanoparticles using the aqueous extract of rose petals. The effects of gold salt concentration, extract concentration and extract quantity were investigated on nanoparticles synthesis. Gold nanoparticles were characterized with different techniques such as UV-vis spectroscopy, FT-IR spectroscopy, X-ray diffraction, energy dispersive X-ray spectroscopy, dynamic light scattering and transmission electron microscopy. Transmission electron microscopy experiments showed that these nanoparticles are formed with various shapes. FT-IR spectroscopy revealed that gold nanoparticles were functionalized with biomolecules that have primary amine group (-NH 2), carbonyl group, -OH groups and other stabilizing functional groups. X-ray diffraction pattern showed high purity and face centered cubic structure of gold nanoparticles. Dynamic light scattering technique was used for particle size measurement, and it was found to be about 10 nm. The rate of the reaction was high and it was completed within 5 min. © 2011 Elsevier B.V. All rights reserved.
Ansari Y., Gerasim D., Mahdavinia M.
Publication Date: 2011
African Journal of Agricultural Research (1991637X)(15)pp. 3619-3622
Although agricultural credit is one of the important issues in agriculture, almost no organized study has been done on caring about the distribution and utilization to achieve the agricultural prosperity and economic growth. This analytic and descriptive study was conducted to explore, that factor affecting the efficiency of agricultural facilities from viewpoint of farmers and credit experts. To achieve the objectives of the study, the survey data were collected by an effective and reliable questionnaire designed to this study. Results indicated that the process of agricultural training, low age and higher education of farmer had a positive significance relationship with effectiveness of their earning facilities on the fields of profit, increasing productions employment, and satisfaction with farming. © 2011 Academic Journals.
Hosseini, S.R., Pouryayevali m.r.,
Publication Date: 2011
Nonlinear Analysis, Theory, Methods and Applications (0362546X)(12)pp. 3884-3895
In this paper, a notion of generalized gradient on Riemannian manifolds is considered and a subdifferential calculus related to this subdifferential is presented. A characterization of the tangent cone to a nonempty subset S of a Riemannian manifold M at a point x is obtained. Then, these results are applied to characterize epi-Lipschitz subsets of complete Riemannian manifolds. © 2011 Elsevier Ltd. All rights reserved.
Khoshnevisan K., Bordbar, A., Zare, D., Davoodi D., Noruzi M., Barkhi M., Tabatabaei, M.
Publication Date: 2011
Chemical Engineering Journal (1385-8947)(2)pp. 669-673
Cellulase on commercial superparamagnetic nanoparticles was characterized by DLS, and TEM methods in relation to their size and structure. The cellulase enzyme was bound via physical adsorption (ionic bound). FTIR spectroscopy confirmed the successful binding of cellulase (endoglucanase) onto the particle, and binding efficiency was determined at 95% using the Bradford method. The maximal enzyme activity was assessed using CMC as the substrate and was 0.1. unit (μmol/min. ml). The adsorption capacity of cellulase onto nanoparticles reached 31. mg/g. The stability of the immobilized enzyme increased in comparison with the free enzyme. Overall, this study showed that that the stability and activity of the cellulase were enhanced via physical adsorption to the magnetic nanoparticles. This suggested that immobilized enzyme on magnetic beads could be used in an interesting range of application allowing both using in broader temperature and pH ranges, facilitating long-term storage, while permitting magnetic recovery of the enzyme for reuse or purification of the product. © 2011 Elsevier B.V.
Hossein, H.H.S., Zarrabi, A., Zarepour, A.
Publication Date: 2017
Journal of Babol University of Medical Sciences (15614107)(6)pp. 64-70
BACKGROUND AND OBJECTIVE: Considering the increasing number of patients with cancer and the relative ineffectiveness of existing treatments, finding a modern technique for cancer treatment has been one of the major topics of research in recent decades. The present study aims to load curcumin anticancer drug on targeted iron oxide nanoparticles. METHODS: In this laboratory research, iron oxide nanoparticles were synthesized using polyol method. Then, they were coated with polyglycerol as a polymeric coating through ring - opening polymerization method. Folic acid (with three weight ratios of 2, 25 and 50%) was used to target the system constructed for specific penetration into the cancer cells. The experiments of loading the drug were performed with three weight ratios of 0.5, 1 and 2 µg nanoparticles on coated and targeted nanoparticles. Then, drug release rate was measured under in vitro conditions. Finally, MTT Assay was used to analyze cell toxicity of the loaded drug. FINDINGS: Results indicated successful construction of 20 nm nanoparticles. The maximum rate of drug loading into the system was about 88 and 82% for non-targeted nanoparticles and targeted nanoparticles, respectively, while increased targeting had adverse effects on drug loading. Moreover, the loaded drug had a more successful therapeutic effect compared with the free drug. CONCLUSION: Results of the study demonstrated that the constructed nanoparticles have the necessary efficiency to act as a system for transferring anticancer drug. © 2017, Babol University of Medical Sciences. All rights reserved.
Sengupta B., Sahihi, M., Dehkhodaei, M., Kelly D., Arany I.
Publication Date: 2017
PLoS ONE (19326203)(6)
Plant flavonoids are well known as antioxidants against oxidative stress induced by exposure to external pollutants. Nicotine (NIC) is one of those agents which increases renal oxidative stress, an important factor in the pathogenesis of renal epithelial injury in smokers. Although several studies had been conducted on flavonoids and oxidative stress, the mechanism of the protective pathways are not fully understood. Here, we present studies on antioxidant properties of two mono-hydroxyflavone isomers, 3-hydroxyflanove (3HF)-and 7-hydroxyflavone (7HF), against nicotine-associated oxidative stress and injury in cultured renal proximal tubule cells and correlate their antioxidant properties with their chemical structure. Our data clearly demonstrates, for the first time, that while both 3HF and 7HF protect renal cells from NIC-associated cytotoxicity, the mechanism of their action is different: 3HF elicits protective activity via the PKA/CREB/MnSOD pathway while 7HF does so via the ERK/Nrf2/HO-1 pathway. Molecular docking and dynamics simulations with two major signaling pathway proteins showed significant differences in the binding energies of 3HF (-5.67 and -7.39 kcal.mol-1) compared to 7HF (-5.41 and -8.55 kcal.mol-1) in the matrices of CREB and Keap1-Nrf2 proteins respectively, which corroborate with the observed differences in their protective properties in the renal cells. The implications of this novel explorative study is likely to promote the understanding of the mechanisms of the antioxidative functions of different flavones. © 2017 Sengupta et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Zonoubi R., Eslami-rasekh, A., Tavakoli, M.
Publication Date: 2017
System (0346251X)pp. 1-12
Teachers' efficacy beliefs exert a significant influence on their practice and their students' learning. This study investigates the contribution of two six-month Professional Learning Community (PLC) interventions to 10 English as a Foreign Language (EFL) novice and experienced teachers' self-efficacy. The data were collected through pre and post-interviews with the participants, their reflective journals, and recordings of the PLC meetings. The findings suggest that the experienced teachers' self-efficacy improved in terms of employing innovative instructional strategies and language proficiency. An increase was also observed in the novice teachers’ self-efficacy for classroom management, their autonomy, and their perceived language proficiency. Finally, the participants in both groups developed a stronger sense of professional community membership as reflected in their focus on their collective efficacy toward the end of the PLCs. © 2017
Peimanifard Z., Rashid-nadimi, S.
Publication Date: 2017
Electrochemistry Communications (13882481)pp. 37-40
A concept for light-powered visual detection of glucose is developed. The detection mechanism is based on pairing a photo-active anode with an electrochromic counter electrode. The photoelectrochemical reaction changes the oxidation state of the analyte, leading to a change in the color of the electrochromic material, which makes visual detection possible. All of the electrical charge required to change the color of the electrochromic material is supplied by the photoelectrochemical reaction powered by visible light, so no conventional energy source is required. The proposed system consists of hematite modified with nickel hydroxide (Ni(OH)2) as the photoanode, and Prussian blue deposited on a fluorine-doped tin oxide electrode as the electrochromic cathode. Under illumination, photo-oxidation of glucose at the photoanode is followed by reduction of Prussian blue to Prussian white at the cathode. The presence of glucose can therefore be detected visually as decolorization of Prussian blue occurs. © 2017 Elsevier B.V.
Keivani M., Mardaneh M., Koochi A., Rezaei M., Abadyan M.
Publication Date: 2016
Physica E: Low-Dimensional Systems and Nanostructures (13869477)pp. 60-69
Herein, the dynamic pull-in instability of cantilever nanoactuator fabricated from conductive cylindrical nanowire with circular cross-section is studied under the presence of Casimir force. The Gurtin-Murdoch surface elasticity in combination with the couple stress theory is employed to incorporate the coupled effects of surface energy and size phenomenon. Using Green-Lagrange strain, the higher order surface stress components are incorporated in the governing equation. The Dirichlet mode is considered and an asymptotic solution, based on the path integral approach, is applied to consider the effect of the Casimir attraction. Furthermore, the influence of structural damping is considered in the model. The nonlinear governing equation is solved using analytical reduced order method (ROM). The effects of various parameters on the dynamic pull-in parameters, phase planes and stability threshold of the actuator are demonstrated. © 2015 Elsevier B.V.
Gholami, M., Talaie m.r., M.R., Aghamiri, S.
Publication Date: 2016
Journal of the Taiwan Institute of Chemical Engineers (18761070)pp. 205-209
In this study, a series of experiments was carried out to find the optimum condition for grafting 3-[2-(2-Aminoethylamino)ethylamino]propyltrimethoxysilane (here after TRI) on bi-modal porous structure MCM-41 (here after BPS-MCM-41). The Taguchi experimental design L9 orthogonal array (OA, three factors in three levels) was applied to investigate the effect of temperature, water to solid support ratio, and TRI to solid support ratio on the amine grafting and CO2 adsorption performance of amine grafted BPS-MCM-41 structure. The ratio of adsorbed CO2 to consumed TRI was selected as the objective function of optimization. The optimum conditions for the BPS-MCM-41 were 85 °C, the water to support ratio of 0.3 cc/g, and the aminosilane to support ratio of 1.5 cc/g. The amine grafting of BPS-MCM-41 in this condition resulted in 2.31 mmol/g adsorption capacity. The analysis of variance (ANOVA) showed that the most significant effect on the response was exerted by the amount of TRI used, while the reaction temperature was found to be the least influential. © 2015 Taiwan Institute of Chemical Engineers.
Mehrnoosh N., Rezaei dolatabadi, H.
Publication Date: 2016
International Business Management (discontinued) (19935250)(5)pp. 611-618
This study analyses the impact of attitudes, subjective norms and perceived behavioral control on information technology adoption and performance of employees. For this purpose, the Theory of Planned Behavior (TPB) is used. In the proposed model, the dependent variable of employee performance was added and the independent variables influence attitudes, subjective norms and perceived behavioral control on the dependent variables of behavioral intention to use IT, the actual use of the system and employee performance is investigated. The statistical population 2160 people of administrative employees of three universities of universities in Isfahan (University of Isfahan, Isfahan University of Technology and University of Khorasgan) is formed. To descriptive analyse the demographic data the statistical methods are used. For article literature, the libraries method and for collecting data, the field method is used. Since, the purpose of this research is particular model test of the relationship between the variables that have with each other causality, analysis method used in this research is Structural Equation Model. Reliability and validity of the PLS Method in two parts is examined: the section on measurement models and the structural model. To check the fit of the first part means models fitting for measuring, the three cases are used: reliability index, convergent validity and divergent validity. The research results confirm the hypothesized model. This study presents results obtained of research are discussed. © Medwell Journals, 2016.
Abedi M., Ghalavand, Y.
Publication Date: 2021
Water Science and Technology: Water Supply (16069749)(7)pp. 3557-3569
One of the important approaches in thermal desalination processes is consumed energy reduction. To achieve this aim, three arrangements of humidification-compression (HC) processes are designed. Two single-stage processes and one double-stage HC process are designed and their performances are compared based on desalinated water production, gained output ratio (GOR) and power consumption. An attempt is made to reduce the power consumption and improve the system performance. All three processes are simulated to examine the effect of operation parameters on HC performance. To validate these simulations, the theoretical results are compared with an experimental rig with a humidifier column of 1.5 m height. The results indicate that the simulation values conform to the experimental data. The effect of minimum approach temperature (ATmin) on system performance is investigated for three processes subject to constant operating conditions (feed temperature, water mass flow, air mass flow, and pressure ratio). For this purpose, four values of ATmin are considered (7.5,10,12.5 and 15 °C) for heat exchanger operations. The results indicate that an increase in ATmin in all three cases increases desalinated water volume and GOR. Also, the double-stage HC system has higher water production rate (66.08 kg/h) and higher GOR (17.19) compared with its counterparts. © 2021 The Authors
Nabi-Afjadi M., Karami H., Goudarzi K., Alipourfard I., Bahreini E.
Publication Date: 2021
Clinical and Molecular Allergy (14767961)(1)
The concern of today's communities is to find a way to prevent or treat COVID-19 and reduce its symptoms in the patients. However, the genetic mutations and more resistant strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge; the designed vaccines and adjuvant therapies would potentially control the symptoms and severity of COVID-19. The most important complication of this viral infection is acute respiratory distress syndrome, which occurs due to the infiltration of leukocytes into the alveoli and the raised cytokine storm. Interferons, as a cytokine family in the host, play an important role in the immune-related antiviral defense and have been considered in the treatment protocols of COVID-19. In addition, it has been indicated that some nutrients, including vitamin D, magnesium and zinc are essential in the modulation of the immune system and interferon (IFN) signaling pathway. Several recent studies have investigated the treatment effect of vitamin D on COVID-19 and reported the association between optimal levels of this vitamin and reduced disease risk. In the present study, the synergistic action of vitamin D, magnesium and zinc in IFN signaling is discussed as a treatment option for COVID-19 involvement. © 2021, The Author(s).
Dadkhah Tehrani R., Givi H., Crunteanu D.-E., Cican G.
Publication Date: 2021
Applied Sciences (Switzerland) (20763417)(21)
In this paper, Predictive Functional Control (PFC) is used for X-Y pedestal control for LEO satellite tracking. According to the nonlinear characteristics of the X-Y pedestal and pedestal model variation caused by its operating point change, the use of system identification algorithm, which is based on special types of orthonormal functions known as Laguerre functions, is presented. This algorithm is combined with PFC to obtain a novel adaptive control algorithm entitled Adaptive Predictive Functional Control (APFC). In this combination, Laguerre functions are utilized for system identification, while the PFC is the control law. An interesting feature of the proposed algorithm is its desirable performance against the interference effect of channel X and channel Y. The proposed APFC algorithm is compared with Proportional Integral Derivative (PID) controller using simulation results. The results confirm that the proposed controller improves the performance in terms of the pedestal model variations; that is, the controller is capable of adapting to the model changes desirably. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Rasaei N., Asbaghi, O., Samadi M., Setayesh L., Bagheri, R., Gholami F., Soveid N., Casazza K., Wong, A., Suzuki, K., Mirzaei K.
Publication Date: 2021
Antioxidants (20763921)(11)
It is well-established that green tea supplementation has antioxidant properties. However, whether green tea supplementation leads to oxidative stress reduction remains unclear, as clinical investigations on this subject have yielded inconsistent outcomes. Consequently, we aimed to determine the effects of green tea supplementation on oxidative stress in adults. A systematic search of English language publications up to 21 August 2021 was carried out in PubMed, Scopus, Embase, and ISI Web of Science, utilizing pertinent keywords. These searches included randomized controlled trials (RCTs) evaluating the relationship between green tea supplementation, malondialdehyde (MDA), and total antioxidant capacity (TAC) in adults. A random-effects model was used to estimate the weighted mean difference (WMD) and 95% confidence intervals (95% CI). Meta-regression and non-linear dose-response analyses were performed to investigate the association between the dosage of green tea (mg/day) and the duration of the intervention (weeks) with pooled effect size. Sixteen RCTs with seventeen arms including 760 participants met the inclusion criteria. Our results indicated that green tea supplementation had significant effects on TAC (weighted mean difference [WMD]: 0.20 mmol/L; 95% CI: 0.09, 0.30, p < 0.001) and significant heterogeneity between studies (I2 = 98.6%, p < 0.001), which was largely related to gender and body mass index (BMI). Subgroup analysis in TAC identified a significant relationship except with low dose supplementation and obese individuals. No relationship between MDA and green tea supplementation was observed in any subgroups; however, meta-regression analysis revealed a linear inverse association between the dosage and significant change in MDA (r = −2117.18, p = 0.017). Our outcomes suggest that green tea supplementation improves TAC and affects MDA based on the dose of the intervention in adults. Future RCTs with longer durations are needed to expand our findings. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Banisi M.K., Ghadri H., Soltani B., Farshid A., Behnam B., Rhouholamini A.A., Mohammadi A., Hamzavi S.F., Azizi A., Deravi N., Noroozi, M., Magsudy A., Seyedipour S., Behzad S., Khakpour Y.
Publication Date: 2025
Langenbeck's Archives of Surgery (14352443)(1)
Purpose: The impact of preoperative MRI on breast cancer recurrence and long-term outcomes remains undefined. Therefore, this study aims at determining the influence of preoperative MRI on in-breast tumor recurrence rates in cases of surgical treatment for breast cancer. Methods: A systematic review and meta-analysis were performed. Literature searches of PubMed, Scopus, and Google Scholar were conducted for studies up to February 2024. Two authors assessed the quality of the eligible studies and extracted their data. Results: The meta-analysis included 14 studies (2 RCTs, 12 cohort studies) with 12,889 patients with 5,451 undergoing preoperative MRI. Pooled hazard ratio for in-breast tumor recurrence was 0.95, using fixed effects and 0.94 using random effects models with 95% confidence intervals of 0.80–1.14 and 0.77–1.14, respectively. A trend towards lower recurrence rates in the MRI group was seen, but the reduction was not statistically significant. Conclusion: This meta-analysis found no significant reduction in in-breast tumor recurrence rates associated with preoperative MRI use in breast cancer patients, consistent with previous findings. © The Author(s) 2025.
Publication Date: 2025
Neurocomputing (9252312)
Multilingual neural machine translation (MNMT) is a novel machine translation approach that benefits from large multilingual resources. However, its performance drops significantly when training with low-resource languages due to the reliance on parameter sharing and data size. In this paper, a new method is proposed to improve the performance of MNMT for a pair of languages where the target language is low-resource. The main idea of this study is to find important nodes that have parameters connected to them that negatively affect an MNMT model and then split those nodes into two sub nodes. Then, the model selects the important sub node that has an effect on the specific language pair to create a twin sub node. This twin sub node helps to strengthen the translation quality of the specific language pair without having a negative effect on other languages. The proposed method works in four steps as: 1) training an MNMT model with parameter sharing over multiple languages, 2) selecting important nodes which negatively affect the MNMT, 3) splitting important nodes into sub nodes, and 4) Twining important sub nodes. The proposed method has been evaluated using several multilingual datasets, including TED 2013, TED 2020, and BIBLE, by examining English-Persian language as a case study. The obtained results show that the proposed method yields the best results for one-to-many and many-to-many models according to the average BLEU value and semantic similarity. The results also show that the proposed method has given better results than other well-known large language models, such as ChatGPT, BING GPT4, and the Google Neural Machine Translation (GNMT) model, when applied to a low-resource language. © 2025 Elsevier B.V.
Alishahi, N.
Publication Date: 2025
Applied Organometallic Chemistry (2682605)(6)
The synthesis, characterization, and catalytic activity of triazine diphosphonium hydrogen sulfate ionic liquid-modified silica-coated magnetic nanoparticles ([APTADP]HSO4@MNPs) are reported. The organized magnetic nanocatalyst was characterized using FT-IR, FE-SEM, SEM–EDX, TEM, VSM, TG/DTG, XRD, and ICP techniques. The activity of this catalyst was evaluated in the synthesis of some novel mono- and bis-phenyl-2-(cyclohexylamino)-2-oxoethyl-2-acetoxybenzoate derivatives as Passerini adducts from cyclohexyl isocynide, different arylaldehydes, and aspirine/benzoic acid derivatives in water. The Passerini additives' composition was determined using spectroscopic procedures like melting point, IR, 1H NMR, 13C NMR, elemental analysis, and MS spectra. Synthesizing a wide variety of biological materials under mild conditions, high yield, and purity due to the simple production process, excellent recovery, and catalyst recycling makes this process attractive and in close agreement with green chemistry. © 2025 John Wiley & Sons Ltd.
