دکتر مهدی کارگرفرد

استاد

گروه فیزیولوژی ورزش
دانشکده علوم ورزشی

پست الکترونیکی

m.kargarfard@spr.ui.ac.ir

تلفن

031 36687572

آدرس

دانشگاه اصفهان میدان آزادی اصفهان، ایران
کد پستی : 8174673441

2009

2025

فعالیت های پژوهشی بر اساس سال

معرفی کلی

درباره من

اینجانب مهدی کارگرفرد، استاد فیزیولوژی ورزشی در دانشکده علوم ورزشی دانشگاه اصفهان هستم . تمام دوران فعالیت علمی خود را وقف درک این موضوع کرده‌ام که چگونه ورزش و فعالیت بدنی می‌تواند سلامت انسان را در گروه‌های مختلف جمعیتی، از افراد سالم تا مبتلایان به بیماری‌های مزمن، بهبود بخشد. دکتری خود را در رشته فیزیولوژی ورزشی دریافت کرده‌ام و به تدریج مراتب علمی را طی کرده‌ام. پیش از این با مرتبه دانشیار فعالیت داشته‌ام و اکنون با مرتبه استادی مشغول به کار هستم . پژوهش‌های من در نقطه تلاقی علم ورزش، توانبخشی بالینی و سلامت عمومی قرار دارد. کار من در سطح بین‌المللی شناخته شده است و تاکنون بیش از ۱۰۰ مقاله علمی منتشر کرده‌ام که نزدیک به ۱,۸۰۰ استناد داشته و شاخص اچ-ایندکس ۲۴ را در پایگاه اسکوپوس برایم به ارمغان آورده است . در گوگل اسکالر نیز شاخص‌های مشابهی با اچ-ایندکس ۲۶ دارم . با پژوهشگرانی از سراسر جهان از جمله آمریکا، مالزی، استرالیا و فرانسه همکاری داشته‌ام . من عمیقاً به تربیت نسل بعدی دانشمندان علوم ورزشی متعهد هستم و پژوهش‌هایی تأثیرگذار انجام می‌دهم که شکاف بین یافته‌های آزمایشگاهی و کاربردهای واقعی در عملکرد ورزشی و توانبخشی را پر می‌کند.

علاقه مندی پژوهشی

فیزیولوژی ورزش قلبی-عروقی: بررسی اثر روش‌های مختلف تمرینی بر ساختار و عملکرد قلب و پاسخ‌های همودینامیک ورزش در بیماری‌های مزمن: مولتیپل اسکلروزیس (MS)، سرطان پستان، دیابت نوع ۲، چاقی و بیماری‌های قلبی-عروقی ورزش در شرایط خاص: بررسی اثر تمرین در محیط‌های آلوده عملکرد ورزشی و تمرین: سازگاری‌های عضلانی، تمرینات مقاومتی و هوازی توانبخشی و ورزش درمانی: تمرینات آبی، توانبخشی قلبی و ارگونومی محیط کار

فیزیولوژی ورزش قلبی-عروقیورزش در بیماری‌های مزمنورزش در شرایط خاصعملکرد ورزشی و تمرینتوانبخشی و ورزش درمانی

عضویت در انجمن ها و گروههای تحقیقاتی

سردبیر – مجله فیزیولوژی ورزشی و عملکرد (دانشگاه آزاد اصفهان)

سردبیر گروه فیزیولوژی ورزشی

فعالیت‌های حرفه‌ای

فیزیولوژی ورزش قلبی-عروقی – عملکرد قلب، پاسخ‌های همودینامیک، متابولیسم گلوکز عملکرد ورزشی و تمرین – پایش بار تمرینی، سازگاری‌های عضلانی، تمرینات مقاومتی توانبخشی و ورزش درمانی – MS (تمرینات آبی)، ارگونومی، توانبخشی قلبی، دیابت/چاقی پزشکی ورزشی و سلامت عمومی – ورزش در هوای آلوده، نشانگرهای التهابی (Irisin)

فیزیولوژی ورزش قلبی-عروقیعملکرد ورزشی و تمرینتوانبخشی و ورزش درمانیپزشکی ورزشی و سلامت عمومی

برونداد‌های پژوهشی

111

همه موارد

107

مقالات

کتاب

2010

2025

مقالات لاتین

2025

Effects of Coenzyme Q10 Supplementation on Physical Function Adaptations to High-Intensity Interval Training in Older Adults

( Article . Gold • Green )

Bagheri, N., Kargarfard, M., Bagheri, R., Dutheil, F.

Publication Date: 2025

Nutrients (20726643)17(24)

Effects of Resistance Training on Muscular Adaptations and Inflammatory Markers in Overweight and Obese Men

( Article . Green )

Bagheri, N., Bagheri, R., Mesinovic, J., Ghobadi, H., Scott, D., Kargarfard, M., Dutheil, F.

Publication Date: 2025

Medicine and Science in Sports and Exercise (15300315)57(3)pp. 600-612

Purpose Obesity may blunt exercise responsiveness to improve muscular adaptations. The effect of resistance training (RT) targeting different body regions on muscle and inflammatory markers is unclear. This study aimed to investigate the impact of upper (upper body exercises), lower (lower body exercises), or combined (upper body + lower body exercises) RT on muscle and inflammatory markers, body composition, and performance in overweight and obese men. Methods Sixty overweight and obese men (age, 31 ± 4 yr) were randomly assigned to one of four groups: upper-body RT (UB; n = 15), lower-body RT (LB; n = 15), combined RT (UB + LB; n = 15), or control (C; n = 15). The training protocol consisted of three exercise sessions per week for 12 wk. Blood samples for measuring serum markers (follistatin, myostatin, C-reactive protein (CRP), adiponectin, tumor necrosis factor (TNF-), and irisin) were obtained at baseline and 48 h after the final training session. Fat mass (FM), body fat percentage, skeletal muscle mass (SMM), and fat-free mass were measured using bioelectrical impedance analysis (InBody 720). Results SMM, fat-free mass, UB and LB strength and power, follistatin, follistatin/myostatin ratio, adiponectin, and irisin significantly increased, whereas FM, body fat percentage, myostatin, CRP, and TNF- significantly reduced from pre- to post-training in all training groups (P < 0.05). Changes in LB muscle power (r = 0.558), both UB (r = 0.518) and LB (r = 0.419) muscle strength, and follistatin (r = 0.545) had moderate positive relationships with ΔSMM, whereas changes in myostatin (r = -0.585) had a moderate negative relationship with ΔSMM. Also, changes in myostatin (r = 0.825) and CRP (r = 0.715) had a strong positive relationship with ΔFM, whereas TNF- (r = 0.467) had a moderate positive relationship with ΔFM. Follistatin (r = -0.789) and adiponectin (r = -0.713) had a strong negative relationship with ΔFM, whereas irisin (r = -0.426) had a moderate negative relationship with ΔFM. Conclusions Combined RT elicits the greatest increases in follistatin, follistatin/myostatin ratio, and adiponectin, and decreases in myostatin and CRP compared with other training groups in overweight and obese men. However, systemic improvements may be achieved through performing UB or LB RT alone. © Lippincott Williams Wilkins.

Elevated risk of possible sarcopenia and weak muscle strength with higher dietary inflammatory index in Iranian breast cancer survivors: a cross-sectional study

( Article . Gold )

Shirinyfard pilehrood, K., Askari, G., Sharifi, M., Kargarfard, M., Saraf-bank, S.

Publication Date: 2025

BMC Nutrition (20550928)11(1)

The Effects of 12 Weeks of Pulsed Magnetic Therapy and Multicomponent Exercise on Bone Markers and Serum Concentration of Sclerostin in Type 2 Diabetic Patients with Osteoporosis

( Article )

Taimouri, M., Dehkordi, K.J., Kargarfard, M., Taghian f., F.

Publication Date: 2025

Iranian Journal of Diabetes and Metabolism (23454008)25(2)pp. 129-143

Background: The current study aimed to ascertain the impact of pulsed magnetic therapy, multicomponent exercise, and a combination of both modalities on bone markers type 2 diabetic patients with osteoporotic. Methods: In a randomized controlled clinical trial study, 56 older patients with type 2 diabetic osteoporosis (age: 68.18±3.67 yr; weight: 78.13±7.65 kg, body mass index: 28.40±1.76 kg/m2) were randomly assigned to either the multicomponent exercise + Full-body pulsed electromagnetic field (MCEx+PEMF, n= 18) multicomponent exercise + placebo full-body PEMF (MCEx+PPEMF, n=17) and a full-body PEMF alone (PEMF, n= 21). PEMF was applied for the whole body using a full-body mat three times per week, 60 minutes for 12 weeks, with a multicomponent exercise protocol that includes flexibility, aerobic exercise, strengthening, weight-bearing, and balance exercises followed by whole-body vibration (WBV) training. The body composition, bone mineral density (BMD), bone metabolism markers (phosphorus, calcium, sclerostin, osteocalcin, Bone-specific alkaline phosphatase (BALP)) before and after the intervention. The data were analyzed using the dependent t test and the two-way repeated measures ANOVA at the level of less than 0.05. Results: After 12 weeks of intervention, there is a significant difference in the serum levels of bone mineral density and bone metabolism markers (phosphorus, calcium, sclerostin, BALP) between the groups (P< 0.05). However, the bonferoni post-test showed an increase in serum levels of BMD, phosphorus, sclerostin, BALP with a significant decrease in calcium in the MCEx+PEMF group in compared to alone PEMF group. Conclusion: The findings showed that the PEMF rehabilitation method combined with multicomponent exercise is more effective and safer than exercise or PEMF only for improving BMD and bone metabolism markers in the type 2 diabetic population with osteoporosis. Therefore, exercise rehabilitation clinics should be encouraged to consider exercise rehabilitation as a treatment method for type 2 diabetic patients with osteoporosis. More studies with long-term follow-up should be considered to confirm these findings. © 2025 Iranian Journal of Diabetes and Metabolism and Tehran University of Medical Sciences.

2024

Association between changes in lean mass, muscle strength, endurance, and power following resistance or concurrent training with differing high protein diets in resistance-trained young males

( Article . Gold )

Bagheri, R., Karimi, Z., Camera, D.M., Scott, D., Bashirzad, M.Z., Sadeghi, R., Kargarfard, M., Dutheil, F.

Publication Date: 2024

Frontiers in Nutrition (2296861X)11

Background: We assessed the relationship of changes in upper and lower body lean mass with muscle strength, endurance and power responses following two high protein diets (1.6 or 3.2 g.kg-1.d−1) during 16 weeks of either concurrent training (CT) or resistance training (RT) in resistance-trained young males. Methods: Forty-eight resistance-trained young males (age: 26 ± 6 yr., body mass index: 25.6 ± 2.9 kg.m−2) performed 16 weeks (four sessions·wk.−1) of CT or RT with either 1.6 g.kg-1.d−1 protein (CT + 1.6; n = 12; RT + 1.6; n = 12) or 3.2 g.kg-1.d−1 protein (CT + 3.2; n = 12; RT + 3.2; n = 12). Relationships between upper (left arm + right arm + trunk lean mass) and lower body (left leg + right leg lean mass) lean mass changes with changes in muscle performance were assessed using Pearson’s correlation coefficients. Results: For upper body, non-significant weak positive relationships were observed between change in upper body lean mass and change in pull-up (r = 0.183, p = 0.234), absolute chest press strength (r = 0.159, p = 0.302), chest press endurance (r = 0.041, p = 0.792), and relative chest press strength (r = 0.097, p = 0.529) while non-significant weak negative relationships were observed for changes in absolute upper body power (r = −0.236, p = 0.123) and relative upper body power (r = −0.203, p = 0.185). For lower body, non-significant weak positive relationships were observed between the change in lower body lean mass with change in vertical jump (r = 0.145, p = 0.346), absolute lower body power (r = 0.109, p = 0.480), absolute leg press strength (r = 0.073, p = 0.638), leg press endurance (r < 0.001, p = 0.998), relative leg press strength (r = 0.089, p = 0.564), and relative lower body power (r = 0.150, p = 0.332). Conclusion: Changes in muscle strength, endurance and power adaptation responses following 16 weeks of either CT or RT with different high protein intakes were not associated with changes in lean mass in resistance-trained young males. These findings indicate that muscle hypertrophy has a small, or negligible, contributory role in promoting functional adaptations with RT or CT, at least over a 16-week period. Copyright © 2024 Bagheri, Karimi, Camera, Scott, Bashirzad, Sadeghi, Kargarfard and Dutheil.